Available Dose Forms of Telmisartan
Telmisartan is available in oral tablet form in three dosage strengths: 20 mg, 40 mg, and 80 mg tablets. 1
Tablet Formulations
Telmisartan tablets have the following specific characteristics:
- 20 mg: White to off-white, uncoated round shaped tablets, flat with beveled edges, plain on one side and debossed "036" on other side 1
- 40 mg: White to off-white, uncoated oval shaped tablets, biconvex with beveled edges, plain on one side and debossed "037" on other side 1
- 80 mg: White to off-white, uncoated oval shaped tablets, biconvex with beveled edges, plain on one side and debossed "038" on other side 1
Dosing Information
Telmisartan tablets can be administered:
- With or without food 1
- Once daily dosing schedule 2
- Starting dose is typically 40 mg once daily for hypertension 1
- Dose range is 20-80 mg for hypertension treatment 1
- For cardiovascular risk reduction, the recommended dose is 80 mg once daily 1
Clinical Considerations
- Most of the antihypertensive effect is apparent within 2 weeks of starting treatment 1
- Maximal blood pressure reduction is generally attained after 4 weeks 1
- No initial dosage adjustment is necessary for elderly patients or patients with renal impairment, including those on hemodialysis 1
- Patients with hepatic insufficiency should start with lower doses and be titrated slowly due to reduced clearance (as telmisartan is eliminated primarily through biliary excretion) 1
Comparative Information
Telmisartan is one of several available angiotensin II receptor antagonists (ARBs) used for hypertension management 2. Unlike some other antihypertensive medications, telmisartan does not have alternative formulations such as oral solutions, extended-release preparations, or injectable forms.
Cautions and Contraindications
- Contraindicated in patients with known hypersensitivity to telmisartan or any component of the product 1
- Should not be co-administered with aliskiren in patients with diabetes 1
- Contraindicated during pregnancy due to potential fetal toxicity 1
Telmisartan's once-daily dosing and availability in multiple strengths allows for convenient administration and dose titration based on clinical response.