When was betamecil first used in ophthalmology in humans?

History of Betamecil in Ophthalmology

Based on the available evidence, there is no record of a drug called "betamecil" ever being used in ophthalmology in humans.

Analysis of Available Evidence

After reviewing all the provided guidelines and research papers, there is no mention of a medication called "betamecil" in any of the ophthalmology literature provided. The evidence covers various aspects of ophthalmological treatments including:

• Management of noninfectious uveitis with immunomodulatory therapy 1
• Corneal edema and opacification management 1
• Diabetic retinopathy standards of care 1
• Retinal vein occlusion treatments 1
• Sjögren's syndrome management with topical therapies 1
• Idiopathic macular hole management 1
• Corneal abrasion management 2
• Various drug classes used in ophthalmology:
  • ACTH in ophthalmology 3
  • NSAIDs in ophthalmology 4
  • Biologic therapy for inflammatory eye conditions 5
  • N-acetylcysteine in ocular therapeutics 6
  • Drug delivery systems for ocular complications 7

Common Medications in Ophthalmology

The evidence discusses several medication classes used in ophthalmology, including:

• Anti-VEGF agents (bevacizumab, ranibizumab, aflibercept) for retinal vein occlusions and diabetic retinopathy 1
• Corticosteroids (triamcinolone, dexamethasone implants) for various inflammatory conditions 1
• Immunomodulatory agents for noninfectious uveitis 1
• Artificial tears and ocular lubricants for dry eye conditions 1
• Topical antibiotics for corneal abrasions 2
• Ocriplasmin for vitreomacular adhesion 1

Potential Confusion

It's possible that "betamecil" might be:

1. A very recently developed drug not yet covered in the literature provided
2. A drug known by a different name in different regions
3. A misspelling or confusion with another medication such as:
   • Betaxolol (a beta-blocker used for glaucoma)
   • Betamethasone (a corticosteroid)
   • Acetylcholine (used during ophthalmic surgery)

Conclusion

There is no evidence in the provided materials that a drug called "betamecil" has ever been used in ophthalmology in humans. If you're looking for information about a specific ophthalmic medication, I would recommend verifying the spelling or providing the drug's generic name or therapeutic class for more accurate information.