From the Research
The 5-year prognosis for well-differentiated intestinal-type sinonasal adenocarcinoma is approximately 68%, based on the most recent and highest quality study available 1.
Key Factors Influencing Prognosis
- Tumor stage at diagnosis
- Extent of surgical resection
- Invasion of critical structures like the skull base, orbit, or brain
- Completeness of tumor removal
- Local recurrence
Treatment and Management
- Surgical resection followed by adjuvant radiation therapy is the typical treatment approach
- Endoscopic transnasal approach is a viable option for selected patients
- Adjuvant radiotherapy is recommended for high-stage and high-grade tumors
Prognostic Factors
- Local recurrence
- Development of distant metastasis
- T classification
- Histopathological classification
- Surgical margins
Important Considerations
- Regular follow-up with endoscopic examinations and imaging studies is essential for at least 5 years post-treatment to monitor for recurrence
- Occupational exposure to wood dust is a known risk factor for this cancer, and patients should avoid such exposures to reduce the risk of developing second primary tumors 2, 1