Do you need to use modifier 25 on both a wellness code and a Nuclear Medicine (NM) visit code for other conditions on the same claim?

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Last updated: August 24, 2025View editorial policy

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Modifier 25 Usage with Wellness and Nuclear Medicine Visit Codes

When billing both a wellness code and a Nuclear Medicine (NM) visit code for other conditions on the same claim, you only need to apply modifier 25 to the E/M service (wellness visit), not to the Nuclear Medicine procedure code. 1

Proper Modifier Application

  • Modifier 25 is specifically designed for use with Evaluation and Management (E/M) services to indicate that a "significant, separately identifiable E/M service" was performed on the same day as a procedure 2, 1
  • The modifier should be appended to the E/M service code (in this case, the wellness visit code) when it's performed on the same day as a procedure or service
  • Nuclear Medicine procedure codes do not require modifier 25 when billed alongside an E/M service

Billing Guidelines for Same-Day Services

  • When billing for both a wellness visit and a Nuclear Medicine procedure on the same date of service:
    • Apply modifier 25 to the wellness visit code to indicate it was a separate and distinct service
    • Bill the Nuclear Medicine procedure code without a modifier (unless other modifiers are required for different reasons)
    • Ensure documentation clearly supports the medical necessity for both services

Documentation Requirements

  • Your documentation must clearly establish that:
    • The wellness visit was a significant, separately identifiable service from the Nuclear Medicine procedure
    • Both services were medically necessary
    • The wellness service was beyond what would normally be included in the Nuclear Medicine procedure 2

Common Pitfalls to Avoid

  • Failing to apply modifier 25 to the E/M service (wellness code) may result in denial of payment for the E/M service
  • Incorrectly applying modifier 25 to the procedure code (Nuclear Medicine) is unnecessary and may trigger claim reviews
  • Insufficient documentation to support the separate nature of both services can lead to claim denials or audits

Reimbursement Implications

  • Proper use of modifier 25 allows for full payment of both the wellness visit and the Nuclear Medicine procedure when performed on the same day
  • Incorrect modifier usage may result in claim denials or reduced payments 1

Following these guidelines ensures proper coding and optimal reimbursement when providing both wellness services and Nuclear Medicine procedures to patients on the same day.

References

Guideline

Modifier Usage Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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