Initial Evaluation and Diagnostic Tests for Right Facial Numbness
CT maxillofacial without IV contrast is the most appropriate initial imaging test for patients presenting with right facial numbness to evaluate for potential structural causes. 1
Initial Assessment Algorithm
Step 1: Clinical Evaluation
- Assess onset and progression of numbness (acute vs. gradual)
- Document distribution pattern (trigeminal nerve divisions affected)
- Check for associated symptoms:
Step 2: Focused Neurological Examination
- Test facial sensation in all three trigeminal divisions (ophthalmic, maxillary, mandibular)
- Assess facial motor function (look for asymmetry or weakness)
- Evaluate other cranial nerves for associated deficits
- Perform Cincinnati Prehospital Stroke Scale (CPSS) to rule out stroke 1:
- Facial droop
- Arm drift
- Abnormal speech
Step 3: Immediate Imaging
For acute onset facial numbness, especially with other neurological symptoms:
- CT maxillofacial without IV contrast is the first-line imaging modality 1
- Consider adding CT head without IV contrast if stroke is suspected 1
Step 4: Additional Testing Based on Clinical Suspicion
MRI with and without contrast if:
- Symptoms persist beyond 2-4 months
- Progressive facial numbness
- Other neurological symptoms present
- History of tumors 2
Trigeminal somatosensory evoked potential (TSEP) and blink reflex (BR) testing if:
- Multiple sclerosis is suspected
- Localization of pontine lesions is needed 3
Clinical Considerations and Pitfalls
Common Causes to Consider
- Stroke: Acute onset with other neurological deficits; requires immediate CT head 1
- Bell's palsy: Associated with facial weakness, typically affects motor more than sensory function 1
- Neoplastic processes: Particularly concerning with progressive symptoms; high mortality rate (57%) in ophthalmology clinic presentations 4
- Cavernous malformations: May present with facial numbness and require MRI for detection 1
- Maxillary sinus pathology: Consider "silent sinus syndrome" with facial numbness and visual symptoms 5
- Metabolic causes: Consider checking magnesium levels, as hypomagnesemia can mimic stroke symptoms 6
Warning Signs Requiring Urgent Evaluation
- Sudden onset numbness (within hours)
- Accompanying weakness or other neurological deficits
- Progressive worsening of symptoms
- History of cancer, especially squamous cell carcinoma 4, 7
Diagnostic Pitfalls to Avoid
- Mistaking normal suture lines for fractures on imaging
- Failing to evaluate the full course of the trigeminal nerve
- Not considering metabolic causes in the absence of structural findings 2, 6
- Overlooking perineural spread from skin cancers, which has poor prognosis 4
Follow-up Recommendations
- If initial imaging is negative but symptoms persist, proceed to MRI with and without contrast
- Consider neurophysiological testing (TSEP, BR) for persistent symptoms with normal imaging 3
- For patients with complete recovery, no additional imaging is typically needed
- For incomplete recovery after 3 months, referral to a specialist is recommended 2
By following this systematic approach to evaluating right facial numbness, clinicians can efficiently identify potentially serious underlying causes and implement appropriate management to improve patient outcomes.