What are the treatment options for tension headaches?

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Last updated: August 25, 2025View editorial policy

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Treatment Options for Tension Headaches

For tension headaches, a combination of acetaminophen with caffeine is recommended as first-line treatment, with ibuprofen and acetaminophen alone also being effective first-line options. 1

Acute Treatment Options

First-Line Medications

  • Acetaminophen with caffeine: Recommended by the American Academy of Family Physicians as first-line treatment due to caffeine's enhancement of analgesic effects 1
  • Acetaminophen 1000 mg: Effective and can be repeated every 6 hours (maximum 4000 mg daily) 1
  • Ibuprofen 400-800 mg: Recommended by VA/DoD guidelines as a first-line treatment 1, 2

Important Medication Considerations

  • Limit use of acute medications to no more than twice weekly to prevent medication overuse headache 1
  • For patients with cardiovascular history, acetaminophen is the safest first-line option 1
  • NSAIDs like ibuprofen carry risks including GI side effects, cardiovascular thrombotic events, and renal effects 2
  • Avoid opioids due to risk of dependency and medication overuse headache 1

Preventive Treatment

When to Consider Prevention

  • If headaches occur more than twice weekly 1
  • If acute treatments are ineffective or contraindicated

Preventive Medication

  • Amitriptyline 50-100 mg daily: First-line preventive therapy for chronic tension-type headache 1, 3
    • Start with lower doses (10 mg three times daily with 20 mg at bedtime) for adolescents and elderly patients 3
    • Monitor for anticholinergic side effects, especially in older patients or those with cardiac comorbidities 1
    • May take up to 30 days to develop full therapeutic effect 3

Non-Pharmacological Approaches

Recommended Non-Drug Treatments

  • Rest in a dark, quiet room 1
  • Ensure adequate hydration 1
  • Physical therapy 1
  • Aerobic exercise or progressive strength training for prevention 1
  • Stress management techniques 1
  • Sleep hygiene optimization 1

Headache Monitoring

  • Track headache patterns (frequency, severity, duration, response to treatment) 1
  • Identify and avoid potential triggers (alcohol, caffeine, certain foods, stress, fatigue) 1

When to Consider Further Evaluation

  • If headaches have atypical features
  • If accompanied by new neurological symptoms
  • If there are worrisome findings on examination
  • In these cases, neuroimaging should be considered 1

Treatment Algorithm

  1. Start with acute treatment:

    • Acetaminophen with caffeine as first choice
    • Alternative first-line options: acetaminophen 1000 mg or ibuprofen 400-800 mg
    • For cardiovascular patients: use acetaminophen alone
  2. If acute treatments fail or headaches occur >2 times/week:

    • Consider preventive therapy with amitriptyline
    • Start low (10-25 mg) and gradually increase to 50-100 mg daily
  3. Implement non-pharmacological approaches alongside medication therapy

  4. Monitor medication use to prevent medication overuse headache (limit to <2 days/week)

Common Pitfalls to Avoid

  • Using acute medications more than twice weekly, which can lead to medication overuse headache
  • Failing to identify and address headache triggers
  • Overlooking the need for preventive therapy in patients with frequent headaches
  • Starting amitriptyline at too high a dose, especially in elderly patients
  • Using opioids for tension headache management

Remember that tension headaches typically present with bilateral, band-like pressure or tightness around the head, often extending to the neck muscles. Proper diagnosis is essential before initiating treatment.

References

Guideline

Tension-Type Headache Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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