What volume of Flonase (fluticasone propionate) to dispense in ml?

Flonase (Fluticasone Propionate) Dispensing Volume

Flonase (fluticasone propionate) nasal spray should be dispensed as a 15.8 mL bottle containing 120 metered sprays at 50 mcg per spray. 1

Standard Dispensing Information

Flonase (fluticasone propionate) nasal spray comes in a standard package with the following specifications:

• 50 mcg per spray
• 120 metered sprays per bottle
• 0.54 FL OZ (15.8 mL) total volume 1

This is the standard dispensing volume for Flonase, which is marketed as FlutiCare in some formulations but contains the same active ingredient (fluticasone propionate) at the same concentration.

Dosing Considerations

The appropriate dosing of Flonase varies by age:

• Adults: 2 sprays per nostril once daily 2
• Children aged 4 years and above: 1 spray per nostril once daily 2, 3
• Children aged 12 years and above: Can use adult dosing of 2 sprays per nostril once daily 3

Administration Technique

For optimal medication delivery:

• Shake the bottle well before use
• Prime the pump when using a new bottle or after not using for a week
• Blow nose gently to clear nostrils before administration
• Aim slightly away from the center of the nose to minimize side effects
• Use the right hand to spray the left nostril and vice versa
• Keep the head upright during administration 3

Common Side Effects

The most common side effects of fluticasone propionate nasal spray include:

• Epistaxis (nosebleeds)
• Headache
• Pharyngitis
• Nasal burning or irritation 2, 3

Clinical Efficacy

Research shows that once-daily dosing of fluticasone propionate is as effective as twice-daily dosing for both seasonal and perennial allergic rhinitis 4, 5. This convenient dosing schedule may improve patient adherence to treatment.

Important Considerations

• A single standard bottle (15.8 mL) provides a 30-day supply for an adult using the recommended dose of 2 sprays per nostril daily
• For children using 1 spray per nostril daily, a single bottle may last up to 60 days
• Multidose vials should be used only for the maximum number of doses specified in the package insert
• Any remaining medication after the maximum number of doses should be discarded 2

When dispensing Flonase, ensure patients understand proper administration technique to maximize efficacy and minimize side effects.