Differential Diagnosis for Asymptomatic Blood in Urine in 2nd Trimester Pregnant Patient

• Single Most Likely Diagnosis
  • Urinary Tract Infection (UTI): This is a common condition in pregnancy due to physiological changes that can predispose to infection, such as ureteral dilation and urinary stasis. Asymptomatic bacteriuria can lead to hematuria.
• Other Likely Diagnoses
  • Kidney Stones: Although less common in pregnancy, kidney stones can cause hematuria. The symptoms might be masked or attributed to the pregnancy itself.
  • Glomerulonephritis: Pregnancy can exacerbate pre-existing glomerulonephritis, leading to hematuria. The condition might be asymptomatic aside from the hematuria.
• Do Not Miss Diagnoses
  • Preeclampsia: Although typically associated with hypertension and proteinuria, preeclampsia can occasionally present with hematuria. Missing this diagnosis could have severe implications for both mother and fetus.
  • Placenta Previa: This condition, where the placenta covers the cervical os, can cause painless vaginal bleeding, which might be mistaken for hematuria if the blood is mixed with urine.
• Rare Diagnoses
  • Renal Cell Carcinoma or Other Genitourinary Cancers: These are rare in young pregnant women but could present with asymptomatic hematuria.
  • Nephrocalcinosis or Other Metabolic Disorders: Conditions affecting calcium metabolism can lead to kidney stones or nephrocalcinosis, causing hematuria.
  • Alport Syndrome or Other Genetic Disorders: These can cause chronic kidney disease and hematuria, potentially being unmasked or worsened during pregnancy.