Emergent Treatment for Pneumoperitoneum
The emergent treatment for pneumoperitoneum with signs of peritonitis is immediate surgical exploration, typically performed by a general surgeon or acute care surgeon. 1
Initial Evaluation and Management
Assessment of Patient Stability
- Evaluate hemodynamic stability (blood pressure, heart rate, lactate levels)
- Assess for signs of peritonitis (diffuse abdominal tenderness, rebound tenderness, guarding)
- Check inflammatory markers (C-reactive protein, procalcitonin) 1
Imaging
- Initial imaging with upright chest X-ray and abdominal X-rays (92% positive predictive value for detecting free air) 1
- If clinical suspicion persists despite normal X-rays, proceed to CT scan
- CT scan is superior for:
- Detecting small amounts of free air
- Identifying perforation source (86% accuracy)
- Evaluating for complications 1
Surgical Management
Timing of Surgery
- Do not delay surgical intervention for imaging studies in hemodynamically unstable patients 1
- Each hour of delay beyond hospital admission decreases survival probability by 2.4% 1
Surgical Approach
Open surgical approach is recommended for:
- Hemodynamically unstable patients
- Patients with diffuse peritonitis
- Toxic megacolon 1
Laparoscopic approach may be considered for:
- Stable patients
- When appropriate surgical expertise exists
- With modifications to reduce aerosolization risk 1
Type of Surgeon
- General surgeons typically perform emergency pneumoperitoneum surgery
- In academic centers, acute care surgeons (specialized in emergency general surgery) often manage these cases
- Colorectal surgeons may be involved when the source is suspected to be colonic 2
Specific Surgical Procedures
Depending on the cause of pneumoperitoneum, the following procedures may be performed:
- For diverticulitis with peritonitis: Hartmann's procedure or primary resection with anastomosis 1
- For colon obstruction or perforation: Loop colostomy or Hartmann's procedure 1
- For perforated peptic ulcer: Primary repair with omental patch
Special Considerations
Non-operative Management
- May be considered in highly selected cases:
- Sealed perforations confirmed by water-soluble contrast studies
- Asymptomatic pneumoperitoneum without signs of peritonitis or sepsis 1
- However, a study showed that in patients with clinical peritonitis, operative treatment was associated with reduced mortality (OR 0.17,95% CI, 0.04-0.80) 3
Elderly Patients
- Patients >70 years have higher mortality if non-operative management fails
- Lower threshold for surgical intervention is warranted 1
Iatrogenic Pneumoperitoneum
- Post-colonoscopy pneumoperitoneum may indicate perforation requiring urgent intervention
- Pneumoperitoneum after PEG tube placement (>50% of cases) is not necessarily a complication requiring intervention 1
Pitfalls and Caveats
- Not all pneumoperitoneum requires surgery - approximately 10% of cases have non-surgical causes 4
- Unnecessary laparotomies can lead to significant morbidity - in one review, 61 of 139 reported cases underwent unnecessary surgical treatment 4
- Delayed diagnosis and treatment significantly increases mortality
- Normal plain radiographs do not exclude pneumoperitoneum; CT should be performed if clinical suspicion persists 1
- In the absence of peritonitis, operative treatment is associated with increased morbidity and non-home discharge 3
Remember that prompt surgical consultation is essential in all cases of pneumoperitoneum, as the surgeon will make the final determination regarding the need for operative intervention based on the clinical presentation and imaging findings.