What are the treatment options for tension headaches?

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Treatment Options for Tension Headache

For tension-type headache, a combination of acetaminophen with caffeine is recommended as first-line treatment, with ibuprofen or acetaminophen alone as effective alternatives. 1

First-Line Pharmacologic Treatment

  • Acetaminophen with caffeine: Recommended by the American Academy of Family Physicians as first-line treatment due to caffeine's enhancement of analgesic effects 1
  • Acetaminophen 1000 mg: Effective and safe option, can be repeated every 6 hours (maximum 4000 mg daily) 1, 2
  • Ibuprofen: Recommended by VA/DoD guidelines as equally effective first-line treatment 1, 2
  • NSAIDs: Various options (aspirin, diclofenac, naproxen) are effective for tension headache 3

Important Dosing Considerations

  • Begin treatment as soon as possible after headache onset
  • Limit use of acute medications to no more than twice weekly to prevent medication overuse headache 1
  • For patients who don't achieve sufficient pain relief, consider increasing dosage without exceeding maximum daily dose 3

Second-Line Treatment Options

For patients who don't respond to first-line treatments:

  • Try a different NSAID or acetaminophen formulation 3
  • Consider combination therapy (NSAID plus acetaminophen) for enhanced efficacy 3, 1

Preventive Treatment

Amitriptyline is the most widely researched and recommended prophylactic medication for frequent tension-type headaches:

  • Indicated when: Headaches occur more than twice weekly or last more than 2 days 4, 5
  • Dosing: Start at low doses (10 mg three times daily with 20 mg at bedtime for elderly/adolescents) 6
  • Maintenance: 50-100 mg daily (some patients respond to 40 mg daily) 6
  • Monitoring: Watch for anticholinergic side effects, especially in older patients 1
  • Duration: Continue maintenance therapy for at least 3 months to reduce relapse risk 6

Non-Pharmacological Approaches

Several evidence-based non-medication options:

  • Resting in a dark, quiet room 1
  • Adequate hydration 1
  • Stress management techniques 1
  • Sleep hygiene optimization 1
  • Physical therapy and trigger point therapy 1, 7
  • Aerobic exercise or progressive strength training 1

Treatment Pitfalls to Avoid

  • Medication overuse headache: Occurs when analgesics are used more than twice weekly; monitor frequency of use carefully 1
  • Opioids and butalbital: Avoid these medications due to risk of dependency and medication overuse headache 3, 1
  • Triptans and ergotamine derivatives: Not first-line for tension headache; contraindicated in patients with CVA history 1
  • Neuroimaging: Generally not needed unless headaches have atypical features or are accompanied by new neurological symptoms 1

Headache Monitoring

  • Track headache patterns (frequency, severity, duration, response to treatment)
  • Identify and avoid potential triggers (alcohol, caffeine, certain foods, stress, fatigue)
  • Consider preventive therapy if headaches occur more than twice weekly 1

By following this structured approach to tension headache management, most patients can achieve significant relief while minimizing the risk of medication overuse and other complications.

References

Guideline

Tension-Type Headache Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Tension-type headache.

American family physician, 2002

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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