Symptoms Consistent with Central Vertigo
Central vertigo is characterized by neurological symptoms including gait disturbances, speech abnormalities, and autonomic dysfunction, which distinguish it from peripheral vertigo causes. 1
Key Clinical Features of Central Vertigo
Neurological Symptoms and Signs
- Gait and speech abnormalities - cerebellar ataxia, dysarthria 2, 1
- Autonomic dysfunction - may be more pronounced than in peripheral causes 2
- Additional neurological deficits - limb ataxia, cranial nerve abnormalities 3
- Headache and vomiting - particularly occipital headache may suggest vertebrobasilar insufficiency 1, 3
Nystagmus Characteristics
- Direction-changing gaze-evoked nystagmus - a key component of the HINTS examination 1
- Positional downbeat nystagmus - present in approximately 69% of central positional vertigo cases 4
- Apogeotropic horizontal nystagmus - seen in about 42% of cases 4
- Multiplanar nystagmus - observed in approximately 23% of cases 4
- Nystagmus that doesn't fatigue - lack of habituation with repeated testing 4
Positional Testing Abnormalities
- Atypical response to Dix-Hallpike maneuver - nystagmus inconsistent with BPPV patterns 5
- Failed response to repositioning maneuvers - persistent symptoms despite appropriate treatment for presumed BPPV 3
- Abnormal HINTS test - particularly important in acute vestibular syndrome 1
Red Flags Suggesting Central Vertigo
- Isolated positional downbeat nystagmus 3
- Apogeotropic horizontal nystagmus on supine roll test without typical BPPV features 3
- Persistent symptoms after appropriate BPPV treatment 2
- Associated auditory or neurological symptoms 2
- Symptoms that don't follow the typical brief, positional pattern of BPPV 4
Diagnostic Considerations
Central vertigo can masquerade as BPPV in approximately 12-20% of positional vertigo cases 5. The HINTS examination (Head-Impulse, Nystagmus, Test of Skew) is particularly valuable for differentiating central from peripheral causes, with abnormal results suggesting central pathology 1.
Common Central Causes of Vertigo
- Posterior circulation stroke/TIA
- Cerebellar tumors
- Cerebellopontine angle tumors
- Multiple sclerosis
- Vascular loops
- Cerebral venous thrombosis
- Obstructive hydrocephalus 3, 5
Clinical Pitfalls to Avoid
- Misdiagnosing central vertigo as BPPV - Strokes presenting with dizziness-vertigo are frequently misdiagnosed in emergency settings 6
- Failing to recognize "red flag" nystagmus patterns - Apogeotropic horizontal and isolated positional downbeat nystagmus should raise suspicion for central pathology 3
- Assuming treatment failure is due to persistent BPPV - Central nervous system disorders explain approximately 3% of BPPV treatment failures 2
- Overlooking subtle neurological signs - Even mild neurological symptoms or signs warrant further investigation 3
When patients present with symptoms consistent with BPPV but do not respond to appropriate repositioning maneuvers after 2-3 attempts, or describe associated auditory or neurological symptoms, they should undergo thorough neurological examination and brain MRI to identify possible central pathology 2.