Discharge Instructions for Patient with Vyvanse-Induced Panic Attack Treated with Lorazepam
Patients who experience a panic attack induced by Vyvanse (lisdexamfetamine) and treated with lorazepam should discontinue Vyvanse immediately, monitor for recurrence of anxiety symptoms for 24-48 hours after lorazepam administration, and follow up with their primary care provider within 1 week.
Medication Management
Vyvanse (Lisdexamfetamine)
- Stop taking Vyvanse immediately until you can discuss with your prescribing physician
- Amphetamines like Vyvanse can cause tachycardia, hypertension, and anxiety symptoms that may precipitate panic attacks 1
- Do not restart this medication without consulting your healthcare provider
Lorazepam
- Take lorazepam only as prescribed for breakthrough anxiety symptoms
- Typical dosing is 0.5-1 mg every 4-6 hours as needed for anxiety 1
- Do not exceed prescribed dose or frequency
- Be aware that benzodiazepines like lorazepam can cause:
- Drowsiness and sedation
- Increased risk of falls
- Potential for dependence with prolonged use 1
- Do not drive or operate machinery while taking lorazepam
- Avoid alcohol and other CNS depressants while taking lorazepam
Monitoring Instructions
- Monitor for recurrence of anxiety symptoms for 24-48 hours after lorazepam administration
- Watch for signs of respiratory depression, especially if additional doses of lorazepam are taken 1
- Be aware that even a single dose of lorazepam can have effects lasting 24-72 hours 2
- If severe anxiety returns after lorazepam wears off, contact your healthcare provider rather than taking additional doses
Warning Signs Requiring Immediate Medical Attention
Seek immediate medical care if you experience:
- Difficulty breathing or shortness of breath
- Chest pain or palpitations
- Severe dizziness or fainting
- Worsening anxiety despite medication
- Thoughts of harming yourself or others
- Confusion or disorientation
Follow-up Care
- Schedule an appointment with your primary care provider within 1 week
- Schedule an appointment with your psychiatrist or the provider who prescribed Vyvanse within 2 weeks
- Bring a list of all medications you are currently taking to your appointments
- Be prepared to discuss alternative treatment options for your original condition that required Vyvanse
Lifestyle Recommendations
- Practice stress-reduction techniques such as deep breathing, progressive muscle relaxation, or mindfulness meditation
- Maintain regular sleep patterns and adequate sleep hygiene
- Avoid caffeine, energy drinks, and other stimulants that may trigger anxiety
- Engage in regular physical activity as tolerated, which can help reduce anxiety symptoms
- Consider cognitive-behavioral therapy (CBT) as a non-pharmacological approach to managing anxiety 3
Additional Information
- Panic attacks, while frightening, are not life-threatening
- The combination of stimulants (like Vyvanse) and anxiety disorders increases the risk of panic attacks
- Benzodiazepines like lorazepam are effective for acute management of panic symptoms but are not recommended for long-term use 4
- Alternative non-stimulant medications may be considered for your underlying condition
Remember that this was likely a medication-induced panic attack, and proper medication adjustment can prevent future episodes. Follow up with your healthcare providers as recommended to develop an appropriate treatment plan.