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Differential Diagnosis for Submental Gland Swelling

Single Most Likely Diagnosis

  • Submandibular sialadenitis: This is the most common cause of submental gland swelling, often due to bacterial or viral infections, which can lead to inflammation of the submandibular gland.

Other Likely Diagnoses

  • Submandibular gland stones (sialolithiasis): Stones in the submandibular gland can cause obstruction and subsequent swelling.
  • Submandibular gland tumors: Both benign (like pleomorphic adenomas) and malignant tumors can present with swelling in the submental area.
  • Dental infections: Infections from the teeth, particularly the lower molars, can spread to the submandibular space and cause swelling.

Do Not Miss Diagnoses

  • Ludwig's angina: A severe infection of the submandibular space that can lead to significant swelling, airway compromise, and is potentially life-threatening if not promptly treated.
  • Necrotizing fasciitis: A rare but deadly infection that can cause rapid progression of swelling and tissue necrosis in the submental area.

Rare Diagnoses

  • Sjögren's syndrome: An autoimmune disorder that can affect the salivary glands, including the submandibular gland, leading to swelling and dry mouth.
  • Sarcoidosis: A condition that can cause inflammation in various parts of the body, including the salivary glands, resulting in swelling.
  • Kimura disease: A rare, chronic inflammatory disorder that can cause swelling in the submandibular area, often associated with lymphadenopathy and eosinophilia.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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