Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: August 28, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Paronychia with Red Streak

  • Single most likely diagnosis
    • Bacterial paronychia: This is the most common cause of paronychia, often resulting from a bacterial infection, typically Staphylococcus aureus. The presence of a red streak suggests the spread of infection, which is consistent with bacterial paronychia.
  • Other Likely diagnoses
    • Fungal paronychia: Caused by fungal infections, this type can also present with redness and swelling, although it tends to be less acute than bacterial paronychia.
    • Herpetic paronychia: Caused by the herpes simplex virus, it can present with pain, swelling, and sometimes a red streak, although vesicles are more characteristic.
    • Irritant or allergic contact dermatitis: While not typically causing a red streak, severe cases can lead to significant inflammation that might be mistaken for an infectious process.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Necrotizing fasciitis: Although rare, this condition is a medical emergency. It can start with symptoms similar to paronychia but rapidly progresses to severe pain, swelling, and necrosis of the skin and underlying tissues.
    • Osteomyelitis: Infection of the bone, which can occur if the infection spreads from the soft tissues around the nail. It requires prompt treatment to prevent serious complications.
    • Sepsis: Any infection, including paronychia, can potentially lead to sepsis if not properly managed, especially in individuals with compromised immune systems.
  • Rare diagnoses
    • Paronychia due to other infectious agents (e.g., Mycobacteria, Blastomyces): These are less common causes of paronychia but should be considered in patients who are immunocompromised or have been exposed to specific pathogens.
    • Erythema elevatum diutinum: A rare skin condition characterized by red, swollen, and tender lesions, which could potentially be mistaken for paronychia with a red streak in some cases.
    • Sarcoidosis: Although extremely rare, sarcoidosis can cause skin lesions around the nails that might resemble paronychia.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.