Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: August 28, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for 66 year old female Nepali with complaints of all over burning of her skin for a year

  • Single most likely diagnosis
    • Diabetes Mellitus: This condition is a common cause of burning skin sensation, especially in older adults. The patient's age and symptoms of burning skin all over her body for a year could be indicative of diabetic neuropathy, a complication of diabetes.
  • Other Likely diagnoses
    • Hypothyroidism: This condition can cause skin symptoms such as burning, itching, or dryness. It is more common in women and can occur at any age, including older adults.
    • Vitamin B12 deficiency: A deficiency in vitamin B12 can cause neurological symptoms, including burning skin sensations. This condition is more common in older adults, especially if they have a poor diet or malabsorption issues.
    • Menopause: Although the patient is 66, some women may still experience menopausal symptoms, including hot flashes and burning skin sensations, even after menopause.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Multiple Myeloma: This is a type of blood cancer that can cause a range of symptoms, including skin burning or itching. Although it is less common, it is a serious condition that requires prompt diagnosis and treatment.
    • Sjögren's syndrome: This autoimmune disorder can cause skin symptoms, including burning or itching, as well as other systemic symptoms. If left untreated, it can lead to serious complications.
    • Peripheral artery disease: This condition can cause burning or itching sensations in the skin, especially in the legs. It is a serious condition that requires prompt diagnosis and treatment to prevent complications such as gangrene or amputation.
  • Rare diagnoses
    • Fabry disease: This is a rare genetic disorder that can cause burning skin sensations, especially in the hands and feet. It is more common in men, but can also occur in women.
    • Erythromelalgia: This is a rare condition that causes burning pain, heat, and redness in the hands and feet. It can be primary (inherited) or secondary (acquired) due to other medical conditions.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.