Differential Diagnosis for Lymph Node in Submental Region with URI
- Single Most Likely Diagnosis
- Reactive lymphadenitis: This is the most likely diagnosis, as the submental lymph node is a common site for reactive lymphadenitis in response to an upper respiratory infection (URI). The proximity of the lymph node to the oral and nasal cavities makes it prone to reacting to infections in these areas.
- Other Likely Diagnoses
- Viral pharyngitis: The submental lymph node can become enlarged in response to viral infections such as mononucleosis or other viral pharyngitides.
- Bacterial pharyngitis: Bacterial infections like streptococcal pharyngitis can also cause lymphadenitis in the submental region.
- Dental infection: Infections of the teeth or gums can drain to the submental lymph nodes, causing lymphadenitis.
- Do Not Miss Diagnoses
- Tuberculosis: Although less common, tuberculosis can cause lymphadenitis in the submental region, and it is crucial to consider this diagnosis, especially in patients with risk factors for TB.
- Lymphoma: Both Hodgkin and non-Hodgkin lymphoma can present with lymphadenopathy, including in the submental region. A thorough evaluation is necessary to rule out these malignancies.
- Cat-scratch disease: This bacterial infection, caused by Bartonella henselae, can lead to lymphadenitis, typically after a cat scratch or bite.
- Rare Diagnoses
- Sarcoidosis: This systemic granulomatous disease can cause lymphadenopathy, including in the submental region, although it is a less common presentation.
- Kikuchi disease: A rare, self-limiting condition that can cause lymphadenitis, often in the cervical region, including the submental area.
- Kimura disease: A rare, chronic inflammatory disorder that can cause lymphadenopathy and eosinophilia, more commonly seen in Asian males.