What is the treatment for cardiac myxoma (a type of benign cardiac tumor)?

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Last updated: March 11, 2025View editorial policy

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From the Guidelines

Surgical excision is the recommended treatment for cardiac myxomas, as it is the most effective way to prevent embolization, cardiac obstruction, and sudden death. Myxomas are benign tumors most commonly found in the heart, particularly in the left atrium, and about 30% to 40% of them embolize, which can lead to ischemic stroke 1. The surgery involves a median sternotomy, cardiopulmonary bypass, and complete removal of the tumor along with a margin of normal tissue to prevent recurrence.

Key Points to Consider

  • The risk of embolization is high, even in asymptomatic patients, making prompt surgical excision necessary 1.
  • Post-surgery, patients typically require 4-6 weeks for recovery and should undergo regular echocardiographic follow-up (usually annually) to monitor for recurrence 1.
  • There is no effective medical therapy or chemotherapy for myxomas, making surgical removal the only viable treatment option 1.
  • The prognosis after complete surgical removal is excellent, with most patients returning to normal life without restrictions 1.

Treatment Approach

The treatment approach for cardiac myxomas should prioritize surgical excision, as it is the most effective way to prevent complications and ensure a favorable outcome. The American Heart Association recommends surgical excision for the treatment of atrial myxomas 1.

Outcome

The outcome of surgical excision for cardiac myxomas is generally excellent, with low recurrence rates and minimal complications. Regular follow-up and monitoring are necessary to ensure the best possible outcome 1.

From the Research

Treatment Overview

  • The primary treatment for cardiac myxoma is surgical removal 2, 3, 4, 5, 6.
  • Surgical excision is considered curative, with few recurrences at long-term follow-up 2, 3.

Surgical Approaches

  • Various surgical approaches can be used, including conventional median sternotomy, minimally invasive, and robotic-assisted approaches 5.
  • The choice of surgical technique should be individualized based on tumor size, location, patient condition, and surgeon expertise 5.
  • Biatrial approach is preferred for left atrial myxomas, providing wider exposure and better outcomes 6.

Outcomes and Complications

  • Surgical excision of cardiac myxoma carries a low operative risk and gives excellent short-term and long-term results 2, 3.
  • Postoperative survival is similar to that of an age- and sex-matched population, with 94% of patients free of recurrent myxomas at 20 years postoperatively 3.
  • Complications can include embolic events, obstruction of the mitral orifice, and low cardiac output syndrome 2, 6.

Follow-up and Monitoring

  • Routine postoperative echocardiographic monitoring is essential to detect residual or recurrent tumors 5, 6.
  • Long-term follow-up is necessary to monitor for potential complications and recurrence 2, 3, 6.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Surgery for cardiac myxomas.

Seminars in thoracic and cardiovascular surgery, 2000

Research

Current diagnosis and management of cardiac myxomas.

Expert review of cardiovascular therapy, 2015

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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