Can patients with a mitral valve (MV) clip undergo Magnetic Resonance Angiography (MRA) of the carotid arteries?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: August 29, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

MRI Safety for Patients with Mitral Valve Clips

Patients with mitral valve clips can safely undergo MRA of the carotid arteries as these devices are MRI-compatible. 1

Safety Considerations for MRI in Patients with MitraClip

The MitraClip device, which is used for transcatheter mitral valve repair (TMVr) in patients with mitral regurgitation, has been specifically approved for cardiac magnetic resonance imaging (MRI). A systematic analysis has demonstrated that cardiac MRI is both feasible and robust in patients who have undergone MitraClip procedures 1.

What to Expect During MRI:

  • A small extinction artifact is typically observed around the clip during MRI
  • This artifact does not interfere with the evaluation of cardiac morphology and function
  • 1.5 Tesla MRI systems have been validated for use in these patients

Clinical Applications

MRI can actually be beneficial for patients with MitraClip as it allows for:

  • Assessment of left ventricular dimensions and function
  • Evaluation of mitral annulus diameter
  • Measurement of left atrial size
  • Monitoring of reverse cardiac remodeling after successful MitraClip placement

MitraClip Device Characteristics

The MitraClip is a polyester fabric-covered cobalt-chromium implant that creates a tissue bridge between the mitral leaflets 2. It functions by:

  • Anchoring flail and/or prolapsed leaflets in degenerative MR
  • Improving coaptation of tethered leaflets in functional MR
  • Creating a double orifice mitral valve

Patient Selection for MitraClip

While not directly related to MRI safety, it's important to note that MitraClip is indicated for:

  • Patients with severe (3+ or 4+) primary degenerative mitral regurgitation who are at prohibitive surgical risk 3
  • Patients with severe secondary mitral regurgitation who remain symptomatic despite optimal medical therapy with LVEF 20-50% and LV end-systolic diameter <70 mm 3

Procedural Considerations

The MitraClip procedure is typically performed:

  • Under general anesthesia
  • Using an antegrade (transseptal) approach
  • With transesophageal echocardiography (TEE) guidance
  • Often requiring placement of 1-2 clips (though up to 4 may be used in some cases) 4

Clinical Outcomes

Successful MitraClip placement has been shown to result in:

  • Reduced mitral regurgitation
  • Improved functional capacity
  • Positive cardiac remodeling that can be monitored with MRI 1

Conclusion for Clinical Practice

When considering MRA of the carotid arteries in patients with MitraClip:

  • No special precautions are needed beyond standard MRI safety protocols
  • The MitraClip device is MRI-compatible and does not pose a safety risk
  • The small artifact around the clip does not significantly interfere with carotid imaging
  • MRI can provide valuable information about both the carotid arteries and cardiac status

This guidance is supported by clinical evidence showing that cardiac MRI is safe and effective in patients with MitraClip devices 1.

References

Research

Cardiac magnetic resonance imaging in patients undergoing percutaneous mitral valve repair with the MitraClip system.

Clinical research in cardiology : official journal of the German Cardiac Society, 2014

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Mitral Regurgitation Treatment Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Related Questions

What is the best algorithm for referring patients for MitraClip (percutaneous mitral valve repair) as a non-invasive cardiologist (Non-Invasive Cardiology)?
Can I administer Glyceryl Trinitrate (GTN) intraoperatively to a patient with Mitral Regurgitation (MR)?
What are the indications for Transcatheter Mitral Valve Replacement (TMVR) with Evoque (Mitral Valve Replacement System)?
Should a 63-year-old male with Heart Failure with Reduced Ejection Fraction (HFrEF) (Diagnosed in 2023, Ejection Fraction 15-20%, Non-Ischemic Cardiomyopathy (NICM), Left Ventricular End-Diastolic Diameter (LVEDD) 7.4cm), history of Cerebrovascular Accident (CVA) (Right Middle Cerebral Artery (R-MCA), Left Hemiplegia, 2023), Chronic Kidney Disease (CKD) (Stage 3b), Hypertension (HTN), Hyperlipidemia (HLD), Right Lower Lobe (RLL) nodule, and malnutrition, who has undergone multiple hospitalizations for Acute Decompensated Heart Failure (ADHF) and is currently on Carvedilol (Beta Blocker) 3.125 mg twice daily, Jardiance (Empagliflozin) 10 mg daily, Valsartan (Angiotensin II Receptor Blocker) 20 mg twice daily, Spironolactone (Aldosterone Antagonist) 12.5 mg daily, and Atorvastatin (HMG-CoA Reductase Inhibitor) 80 mg daily, with significant Left Ventricular (LV) dysfunction, severe Mitral Regurgitation (MR), and unable to tolerate further Guideline-Directed Medical Therapy (GDMT) due to hypotension, be considered for a MitraClip procedure?
What is the role of MitraClip (mitral clip) in treating primary and secondary Mitral Regurgitation (MR)?
What are the treatment options for elderly patients with gait abnormalities?
What is the recommended dosage of doxycycline (antibiotic) for adults?
What is the significance of low urine specific gravity and hypernatremia in an obese patient on lisinopril (Angiotensin-Converting Enzyme inhibitor, ACE inhibitor) and lithium, presenting with urinary frequency and polyuria, despite normal HbA1c levels?
What is the recommended dosage of low dose doxycycline (antibiotic) for treating conditions like acne or rosacea?
What test best indicates immunity to measles?
Can Angiotensin-Converting Enzyme (ACE) inhibitors cause hyponatremia?

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.