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Differential Diagnosis for Hair Loss in a 28-year-old Male

Single Most Likely Diagnosis

  • Androgenetic Alopecia (Male Pattern Baldness): This is the most common cause of hair loss in young males, characterized by a receding hairline and thinning of hair on the vertex of the scalp. It is due to the sensitivity of scalp hairs to dihydrotestosterone (DHT), a potent form of testosterone.

Other Likely Diagnoses

  • Alopecia Areata: An autoimmune condition that leads to patchy hair loss. It can occur at any age and is often associated with other autoimmune diseases.
  • Telogen Effluvium: A condition that causes excessive hair shedding after a major body stress, such as severe illness, psychological stress, or major surgery. It can also be triggered by hormonal changes.
  • Tinea Capitis (Ringworm of the Scalp): A fungal infection that causes hair loss, often accompanied by redness, itching, and scaling of the scalp.
  • Seborrheic Dermatitis: A skin condition that can cause scaly patches, red skin, and stubborn dandruff, leading to hair loss if left untreated.

Do Not Miss Diagnoses

  • Thyroid Disorders (Hypothyroidism or Hyperthyroidism): Both underactive and overactive thyroid glands can cause hair loss among other symptoms. Early detection is crucial for treatment and prevention of long-term complications.
  • Syphilis: A sexually transmitted infection that can cause hair loss in its secondary stage, along with other systemic symptoms.
  • Autoimmune Disorders (e.g., Lupus): Systemic lupus erythematosus and other autoimmune diseases can cause hair loss as part of their broader symptomatology.

Rare Diagnoses

  • Trichotillomania: A psychological disorder characterized by an irresistible urge to pull out one's own hair, leading to noticeable hair loss.
  • Loose Anagen Syndrome: A rare condition where the hair follicles are abnormal, leading to excessive hair shedding.
  • Congenital Hair Loss Conditions (e.g., Congenital Atrichia): Extremely rare conditions present at birth that result in little to no hair growth.
  • Hair Loss due to Medication Side Effects: Certain medications, such as those used for cancer, arthritis, depression, and high blood pressure, can cause hair loss as a side effect.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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