From the Guidelines
The Priorix vial from GSK contains 1 dose of the measles, mumps, and rubella (MMR) vaccine. According to the most recent guidelines from 2022, PRIORIX is supplied as a single-dose vial of lyophilized antigen to be reconstituted with the accompanying prefilled syringe of sterile water diluent 1.
Key Points
- A single dose after reconstitution is approximately 0.5 mL.
- The vaccine is formulated without preservatives and is administered as a subcutaneous injection.
- For routine vaccination, 2 doses are recommended, the first at age 12–15 months, and the second at age 4–6 years 1.
Clinical Considerations
- Healthcare providers should ensure proper reconstitution technique and maintain the cold chain to preserve vaccine efficacy.
- The MMR vaccine provides protection against three serious viral diseases through a single injection, making it an efficient method of immunization.
- It is essential to follow the recommended storage and handling procedures to ensure the vaccine's potency and safety.
From the Research
Number of Doses in a Priorix Vial
- The provided studies do not directly mention the number of doses in a Priorix (Measles, Mumps, and Rubella vaccine) vial from GlaxoSmithKline (GSK) 2, 3, 4, 5, 6.
- However, the studies discuss the immunogenicity and safety of the Priorix vaccine in various age groups and administration routes, indicating that it is a single-dose vaccine or a two-dose vaccine depending on the vaccination schedule 4, 5.
- The exact number of doses in a vial is not specified in the provided evidence, suggesting that this information may not be directly related to the immunogenicity and safety studies of the Priorix vaccine 2, 3, 4, 5, 6.
Vaccine Administration and Dosage
- The Priorix vaccine is administered in a single dose or two doses, depending on the vaccination schedule and age group 4, 5.
- The vaccine can be administered intramuscularly or subcutaneously, with similar reactogenicity profiles and immunogenicity results 6.
- The studies do not provide information on the number of doses in a Priorix vial, which may be relevant for vaccination programs and vaccine distribution 2, 3, 4, 5, 6.