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Differential Diagnosis for Blood in Urine

Single Most Likely Diagnosis

  • Urinary Tract Infection (UTI): This is often the most common cause of hematuria (blood in urine), especially in women. UTIs can cause inflammation and irritation in the urinary tract, leading to bleeding.

Other Likely Diagnoses

  • Kidney Stones: Stones in the kidney or bladder can cause bleeding due to the irritation and damage they inflict on the urinary tract lining.
  • Benign Prostatic Hyperplasia (BPH): Enlargement of the prostate gland can lead to urinary retention and bleeding, especially in older men.
  • Cystitis: Inflammation of the bladder, which can be caused by infections, irritants, or other factors, leading to hematuria.

Do Not Miss Diagnoses

  • Bladder Cancer: Although less common, bladder cancer is a critical diagnosis not to miss, as it can present with painless hematuria.
  • Kidney Cancer: Similar to bladder cancer, kidney cancer can cause hematuria and is crucial to diagnose early for effective treatment.
  • Trauma: Physical injury to the urinary tract, such as from a car accident or a fall, can cause bleeding and must be promptly identified and treated.

Rare Diagnoses

  • Alport Syndrome: A genetic disorder affecting the type IV collagen in the body, leading to kidney disease, hearing loss, and eye abnormalities, and can cause hematuria.
  • Goodpasture Syndrome: A rare autoimmune disease that can cause kidney inflammation and bleeding, often accompanied by lung hemorrhage.
  • Sickle Cell Disease: A genetic disorder that affects hemoglobin production, can cause episodes of hematuria due to sickling of red blood cells in the kidneys.
  • Nephrocalcinosis: A condition characterized by the deposition of calcium salts in the renal tissue, which can lead to hematuria among other symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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