Treatment Options for Various Types of Pain
For most types of pain including abdominal pain, period pain, muscular cramps, headaches, earaches, and toothaches, non-opioid analgesics such as acetaminophen (paracetamol) and NSAIDs like ibuprofen should be used as first-line treatment, with ibuprofen 400-600mg every 6-8 hours being particularly effective for inflammatory pain. 1
First-Line Treatments
Non-Opioid Analgesics
Acetaminophen (Paracetamol)
- Dosage: 650mg every 4-6 hours
- Maximum daily dose: 3-4g
- Best for: Mild pain, headaches, toothaches, earaches
- Caution: Liver toxicity at high doses 1
NSAIDs
- Ibuprofen
- Dosage: 400-600mg every 6-8 hours
- Maximum daily dose: 3200mg
- Take with food to minimize GI effects 2
- Naproxen
- Dosage: 250-500mg twice daily
- Maximum daily dose: 1000mg
- Best for: Inflammatory pain, period pain, muscular cramps, bone pain 3
- Caution: GI toxicity, renal toxicity, cardiovascular risks 1
- Ibuprofen
For Specific Pain Types
Period Pain (Dysmenorrhea)
- NSAIDs are first-line treatment
- Heat therapy - Applied to lower abdomen 4
- Hormonal contraceptives - For recurrent, severe dysmenorrhea 6
Muscular Cramps and Spasms
- NSAIDs - Ibuprofen 400-600mg every 6-8 hours 1
- Muscle relaxants - For severe spasms (if NSAIDs insufficient)
- Physical therapy - Core strengthening and flexibility exercises 1
Headaches
- Acetaminophen - 650mg every 4-6 hours 1
- NSAIDs - Ibuprofen 400mg or naproxen 500mg for tension or inflammatory headaches
- Combination products - For moderate headaches unresponsive to single agents
Earaches
- Acetaminophen - 650mg every 4-6 hours 1
- NSAIDs - Ibuprofen 400mg every 6 hours
- Topical analgesics - Prescription ear drops with benzocaine if appropriate
Toothaches
- NSAIDs - Ibuprofen 400-600mg every 6 hours 1
- Acetaminophen - 650mg every 4-6 hours
- Topical analgesics - Benzocaine gel applied directly to affected area
Abdominal Pain
- NSAIDs - Ibuprofen 400mg every 6 hours (if not contraindicated) 1
- Acetaminophen - 650mg every 4-6 hours
- Antispasmodics - For cramping pain
Second-Line Treatments
For Moderate Pain Unresponsive to First-Line Treatments
- Weak Opioids (combined with non-opioids)
- Codeine + acetaminophen
- Tramadol
- Caution: Risk of dependence, respiratory depression 1
For Neuropathic Pain Components
- Anticonvulsants: Gabapentin, pregabalin
- Antidepressants: Duloxetine, amitriptyline 1
Interventional Approaches for Refractory Pain
- Transcutaneous electrical nerve stimulation (TENS) 1
- Nerve blocks - For localized, severe pain unresponsive to medications 3
- Physical therapy - Particularly for muscular pain and cramps 1
Important Considerations
Medication Administration
- Take NSAIDs with food to minimize GI side effects 2
- Use the lowest effective dose for the shortest duration 2
- Regular scheduled dosing is more effective than as-needed for chronic pain 1
Monitoring and Cautions
- Monitor for GI bleeding with NSAIDs, especially in elderly patients
- Avoid NSAIDs in patients with renal impairment, heart failure, or GI ulcers
- Limit acetaminophen in patients with liver disease 1
- Avoid prolonged opioid use due to risk of dependence 1
Non-Pharmacological Approaches
- Heat therapy - Particularly effective for dysmenorrhea and muscle pain 4
- Physical exercise - Can reduce dysmenorrhea severity 4
- Proper body mechanics - For prevention of muscular pain 1
By following this stepwise approach to pain management, most types of pain can be effectively controlled while minimizing risks of adverse effects and dependence. The key is to match the analgesic strategy to the type and severity of pain while considering individual patient factors.