Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: September 2, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Seizures, Nausea, and Vomiting

Single Most Likely Diagnosis

  • Migraine with Aura: This condition can present with seizures (especially if the patient has a history of epilepsy or is prone to migraines that can trigger seizure-like activity), nausea, and vomiting. The aura phase of a migraine can sometimes be mistaken for or trigger seizure activity.

Other Likely Diagnoses

  • Gastroenteritis: Infections of the gastrointestinal tract can lead to nausea, vomiting, and in severe cases, dehydration, which might precipitate seizures in susceptible individuals.
  • Food Poisoning: Similar to gastroenteritis, food poisoning can cause severe nausea and vomiting, potentially leading to dehydration and electrolyte imbalances that could trigger seizures.
  • Medication Side Effects: Certain medications can cause seizures, nausea, and vomiting as side effects, especially if the patient is sensitive or has taken an overdose.

Do Not Miss Diagnoses

  • Meningitis or Encephalitis: These are infections of the brain and meninges that can present with seizures, nausea, vomiting, and fever. Missing these diagnoses can be fatal.
  • Subarachnoid Hemorrhage: A sudden, severe headache (often described as "the worst headache" ever experienced) can be accompanied by nausea, vomiting, and seizures due to the increased intracranial pressure and potential irritation of the brain.
  • Hyponatremia: A condition where the sodium levels in the blood are too low, which can cause seizures, nausea, and vomiting. It's crucial to identify and treat promptly to avoid severe complications.

Rare Diagnoses

  • Reye's Syndrome: A rare but serious condition that causes swelling in the liver and brain. It can occur in children and teenagers recovering from a viral infection, and it's associated with the use of aspirin. Symptoms include seizures, nausea, vomiting, and confusion.
  • Cyclic Vomiting Syndrome: A disorder that causes recurrent episodes of severe nausea and vomiting, which can be so severe as to potentially trigger seizures in susceptible individuals due to dehydration and electrolyte imbalances.
  • Porphyrias: A group of rare disorders that can cause a variety of symptoms, including seizures, nausea, vomiting, and abdominal pain, due to the accumulation of natural chemicals that produce porphyrin in the body.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.