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Differential Diagnosis for Lower Back Pain with Radiation to Groin

  • Single most likely diagnosis
    • Lumbar Herniated Disc: This is the most common cause of lower back pain radiating to the groin due to the compression of nerve roots, particularly L2-L4, which can refer pain to the groin area.
  • Other Likely diagnoses
    • Lumbar Spondylosis: Degenerative changes in the lumbar spine can cause pain radiating to the groin due to foraminal stenosis or facet joint osteoarthritis.
    • Piriformis Syndrome: Although more commonly associated with sciatic pain, in some cases, the piriformis muscle can compress nerves that refer pain to the groin.
    • Osteitis Condensans Ilii: A condition characterized by increased bone density in the ilium, often associated with lower back pain and sometimes radiating pain to the groin.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Abdominal Aortic Aneurysm (AAA): A potentially life-threatening condition that can cause lower back pain radiating to the groin, especially if the aneurysm is expanding or leaking.
    • Kidney Stones: Severe pain from kidney stones can radiate from the flank to the groin and must be promptly diagnosed and treated.
    • Spinal Infection (e.g., Discitis, Osteomyelitis): Infections of the spine can cause severe back pain and may radiate to the groin, requiring urgent medical attention.
    • Spinal Tumors: Both primary and metastatic tumors can cause back pain radiating to unusual areas, including the groin, and are critical to diagnose early.
  • Rare diagnoses
    • Referred Pain from Intra-abdominal Pathology: Certain conditions like pancreatitis or inflammatory bowel disease can refer pain to the lower back and groin.
    • Nerve Entrapment Syndromes (e.g., Ilioinguinal or Iliohypogastric Nerve Entrapment): These can cause pain in the groin area and sometimes lower back pain, depending on the nerve involved.
    • Facet Joint Cysts: Rarely, cysts can form on the facet joints of the spine and compress nerves, leading to radiating pain.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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