What is the cause of a popping sound when auscultating (listening to) the lungs, distinct from crackles or rales?

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Last updated: March 12, 2025 • View editorial policy

Differential Diagnosis for Popping Sound when Listening to Lungs

  • Single most likely diagnosis + Pneumothorax: A popping sound, often described as a "Hamman's sign" or "mediastinal crunch," can be heard in cases of pneumothorax, particularly when there is air in the mediastinum (pneumomediastinum). This sound is synchronous with the heartbeat and can be a significant clue to the diagnosis.
  • Other Likely diagnoses + Pleural effusion: While not typically associated with a popping sound, a large pleural effusion can sometimes cause unusual sounds due to the movement of fluid or air within the pleural space. + Bronchopleural fistula: This condition, which involves an abnormal connection between the bronchial tree and the pleural space, can lead to unusual sounds, including popping or bubbling, due to air moving through the fistula.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.) + Tension pneumothorax: Although similar to pneumothorax, tension pneumothorax is a medical emergency that requires immediate recognition and treatment. The popping sound could be an initial clue, but it's crucial to identify the increasing pressure and its effects on breathing and circulation. + Esophageal rupture: This condition can lead to air in the mediastinum, potentially causing a popping or crunching sound (Hamman's sign) similar to that heard in pneumomediastinum. It's a serious condition that requires prompt diagnosis and treatment.
  • Rare diagnoses + Catamenial pneumothorax: A rare condition associated with the menstrual cycle, where air enters the pleural space, potentially causing unusual sounds. + Lymphangioleiomyomatosis (LAM): A rare lung disease that can lead to the formation of cysts and potentially pneumothoraces, which might cause unusual lung sounds, including popping.

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