Instructions for Using Boric Acid Vaginal Suppositories
For non-albicans Candida vulvovaginal infections, particularly C. glabrata, use 600 mg boric acid vaginal suppositories once daily for 14 days. 1
When to Use Boric Acid Suppositories
Boric acid suppositories are primarily indicated for:
- Treatment of non-albicans Candida vulvovaginal infections, particularly C. glabrata
- Recurrent vulvovaginal candidiasis that has failed standard azole therapy
- Cases where conventional treatments with fluconazole or other azoles have been unsuccessful
Dosage and Administration
- Standard dosage: 600 mg boric acid in a gelatin capsule inserted vaginally once daily for 14 days 1
- For severe or persistent infections: Some cases may require twice daily dosing (morning and bedtime) 2
- Insertion technique:
- Wash hands thoroughly before and after insertion
- Insert the suppository deep into the vagina using your finger
- Remain lying down for 15-30 minutes after insertion if possible
- Use at bedtime for convenience (to minimize leakage)
Important Precautions
- External use only: For vaginal use only, not for oral consumption 3
- Pregnancy warning: Should not be used during pregnancy 3
- Breastfeeding: Consult healthcare provider before use if breastfeeding 3
- Duration of treatment: Complete the full 14-day course even if symptoms improve earlier
- Side effects: May cause mild vaginal irritation or burning sensation 3
When to Stop and Seek Medical Attention
Stop using boric acid suppositories and consult a healthcare provider if:
- Symptoms persist or worsen after 7 days of use 3
- Inflammation increases 3
- Abdominal pain develops 3
- Foul-smelling discharge occurs 3
- Fever or other systemic symptoms develop
Effectiveness and Expected Results
- For C. glabrata infections: Approximately 70% mycological cure rate at 15 days 4
- Long-term efficacy: About 63% of patients remain cured at 3 months after treatment 5
- Boric acid shows significantly higher cure rates for C. glabrata compared to fluconazole (63.6% vs 28.6%) 4
Follow-Up Recommendations
- No routine follow-up is necessary if symptoms resolve 1
- Return for evaluation if symptoms persist or recur after completing treatment
- For recurrent infections, maintenance therapy may be needed
Additional Considerations
- Boric acid has shown low potential for developing resistance, making it a good option for recurrent infections 6
- Keep out of reach of children as it can be toxic if swallowed 3
- Do not use if you have never had a vaginal yeast infection diagnosed by a doctor 3
- Avoid sexual intercourse during treatment or use condoms to prevent irritation and reinfection
Boric acid suppositories are particularly valuable for treating non-albicans Candida species that are often resistant to conventional azole treatments, providing an important alternative therapeutic option.