Treatment of Blood-Filled Bullae in the Metatarsal Arch
For blood-filled bullae in the metatarsal arch, the primary treatment is to drain the blister while leaving the roof intact, followed by appropriate offloading of the affected area using a non-removable knee-high device if possible.
Initial Management
Blister Management
- Drain but preserve the blister roof:
- Pierce large blisters with a sterile needle to release fluid while keeping the blister roof intact as it forms a natural protective dressing 1
- Leave small to medium blisters intact if they're not causing significant discomfort 1
- Only remove loose, fluttering skin after the blister has broken naturally 1
Wound Care
- Clean the area with antiseptic solution if there are signs of infection
- For painful areas, consider covering with low-adhesion dressings such as Mepitel or Atrauman 1
- If extensive erosions are present, antiseptic baths (e.g., potassium permanganate) or antiseptic-containing bath oils may help dry lesions and prevent infection 1
Offloading Interventions
Primary Offloading Options
First-line treatment: Non-removable knee-high offloading device
- Total contact cast (TCC) or non-removable knee-high walker 1
- Choose based on patient factors and local resources
- Most effective for promoting healing and preventing recurrence
Second-line treatment (if non-removable device is contraindicated or not tolerated):
- Removable knee-high or ankle-high offloading device 1
- Encourage consistent use during all weight-bearing activities
Third-line treatment (if offloading devices unavailable):
- Felted foam in combination with appropriate footwear 1
Important Considerations
- Do not use conventional or standard therapeutic footwear alone as primary treatment 1
- Consider a shoe lift on the contralateral limb to improve comfort and balance 1
- For diabetic patients with infection, adjust offloading approach based on infection severity:
Surgical Interventions (for Persistent Cases)
If non-surgical offloading fails to heal the ulcer, consider surgical options:
For metatarsal head ulcers:
For hallux ulcers:
Monitoring and Follow-up
- Regular assessment of wound healing progress
- Document wound size, surrounding cellulitis, and quality/quantity of drainage 1
- Use a sterile, blunt metal probe to measure wound depth and check for foreign bodies or bone involvement 1
- Adjust treatment based on healing progress
Special Considerations
For diabetic patients: Assess vascular supply before any intervention 1
- Check dorsalis pedis and posterior tibial pulses
- Consider additional vascular testing if pulses are diminished
For hyperkeratosis (common in metatarsal area):
For signs of infection: Obtain appropriate cultures before starting antibiotics and treat according to culture results 1
Remember that proper offloading is the cornerstone of treatment for blood-filled bullae in the metatarsal arch, with the goal of preventing recurrence and promoting healing while minimizing the risk of infection and further tissue damage.