What is the treatment plan for a pressure injury?

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Last updated: September 3, 2025View editorial policy

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Treatment Plan for Pressure Injuries

The treatment of pressure injuries requires a multidisciplinary approach focusing on wound care, nutritional support, and pressure redistribution, with specific interventions tailored to the injury stage. 1

Assessment and Classification

  • Pressure injuries are classified into four stages based on depth of tissue damage:

    • Stage 1: Non-blanchable erythema of intact skin
    • Stage 2: Partial-thickness skin loss with exposed dermis
    • Stage 3: Full-thickness tissue loss exposing subcutaneous fat
    • Stage 4: Full-thickness tissue loss with exposed bone, tendon, or muscle 1
  • Document size, location, and characteristics of the wound including:

    • Wound dimensions (length, width, depth)
    • Presence of undermining or tunneling
    • Wound bed characteristics (granulation, slough, necrotic tissue)
    • Exudate amount and characteristics
    • Signs of infection 1

Treatment Algorithm by Stage

Stage 1-2 Pressure Injuries

  1. Wound cleansing:

    • Clean with normal saline solution
    • Avoid antiseptics that may damage granulation tissue 2
  2. Dressing selection:

    • Use hydrocolloid or foam dressings to reduce wound size (weak recommendation, low-quality evidence) 3
    • For stage 2 injuries with light to moderate exudate, hydrocolloid dressings are recommended
    • Change dressings according to manufacturer recommendations and exudate levels 1
  3. Pressure redistribution:

    • Implement turning schedule every 2 hours
    • Use specialized support surfaces (air-fluidized beds have moderate-quality evidence for reducing ulcer size) 3, 1

Stage 3-4 Pressure Injuries

  1. Debridement:

    • Remove necrotic tissue and biofilm
    • Methods include sharp debridement (preferred for extensive necrosis), enzymatic, or mechanical debridement 1, 2
    • Prompt debridement is essential for infected wounds 2
  2. Wound management:

    • For moderate to heavy exudate: Use alginate or hydrofiber dressings
    • Consider antimicrobial dressings if signs of local infection or biofilm are present 1
    • Electrical stimulation may accelerate wound healing as adjunctive therapy (moderate-quality evidence) 3
  3. Infection management:

    • Monitor for signs of local infection (increased pain, erythema, edema, purulent drainage, malodor)
    • Assess for biofilm formation (delayed healing despite care, poor granulation)
    • Evaluate for osteomyelitis in stage 4 injuries (prevalence 17-58%) 1
    • Systemic antibiotics only when clear evidence of infection exists 1, 4
  4. Surgical consultation:

    • Consider if wound fails to improve with conservative management
    • Appropriate for stage 4 injuries with bone exposure or extensive undermining 1

Nutritional Support

  • Provide protein or amino acid supplementation to reduce wound size (weak recommendation, low-quality evidence) 3
  • Ensure dietary intake of 30-35 kcal/kg/day and 1.25-1.5 g protein/kg/day 1
  • Supplement micronutrients that enhance wound healing (vitamin B6, B12, folate, zinc, vitamin C, vitamin D) 1
  • Maintain adequate hydration 1

Monitoring and Follow-up

  • Regularly reassess wound characteristics to evaluate healing progress
  • Document changes in wound size, depth, and appearance
  • Adjust treatment plan if healing is not progressing as expected
  • Continue pressure redistribution measures even after healing 1

Common Pitfalls to Avoid

  • Misclassifying darkly pigmented skin where erythema may be difficult to detect
  • Using inappropriate dressings for wound type and exudate level
  • Failing to address nutritional deficiencies
  • Overusing antibiotics without clear evidence of infection
  • Inadequate pressure redistribution 1
  • Neglecting to evaluate for biofilm formation, especially in stages 3 and 4 1

By following this structured approach to pressure injury management, clinicians can optimize wound healing, reduce complications, and improve patient outcomes.

References

Guideline

Pressure Injury Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Pressure ulcers. Local wound care.

Clinics in geriatric medicine, 1997

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Pressure ulcers. Physical, supportive, and local aspects of management.

Clinics in podiatric medicine and surgery, 1991

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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