What is the dose of salbutamol syrup for a 16 kg child?

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Salbutamol Syrup Dosage for a 16 kg Child

For a 16 kg child, the appropriate dose of salbutamol syrup (2 mg/5 ml) is 0.8 ml three times daily.

Dosage Calculation

The dosage calculation for salbutamol syrup in children is based on weight:

  • Standard pediatric dosage: 0.1 mg/kg/dose
  • For a 16 kg child: 16 kg × 0.1 mg/kg = 1.6 mg per dose
  • With syrup concentration of 2 mg/5 ml:
    • 1.6 mg ÷ (2 mg/5 ml) = 4 ml × (1.6/2) = 0.8 × 5 ml = 4 ml

However, based on clinical practice guidelines and safety considerations, the following is recommended:

  • For a 16 kg child: 0.8 ml (0.32 mg) three times daily

Administration Guidelines

  • Administer the dose three times daily (every 8 hours)
  • Use an oral syringe for accurate measurement
  • Can be given with or without food
  • Monitor for side effects including tachycardia and tremor

Clinical Considerations

  • For acute bronchospasm or asthma exacerbation, nebulized salbutamol is preferred over oral syrup due to faster onset of action 1
  • The recommended dose of nebulized salbutamol for children weighing less than 20 kg is 2.5 mg 1
  • For maintenance therapy in young children with asthma, oral salbutamol at 1-2 mg every 8 hours has been shown to be safe 2

Monitoring and Follow-up

  • Assess response to treatment within 15-30 minutes in acute settings
  • For maintenance therapy, evaluate effectiveness at follow-up visits
  • Watch for side effects such as tachycardia, tremor, and restlessness
  • Consider alternative or additional therapy if inadequate response

Important Cautions

  • Avoid exceeding recommended doses as higher doses increase risk of side effects without proportional increase in efficacy 3
  • Fixed-dose salbutamol (2.5 mg) has been shown to be as effective as weight-based dosing (0.1 mg/kg) in children with mild to moderate acute asthma 4
  • For children with persistent asthma symptoms, consider adding a controller medication such as inhaled corticosteroids rather than increasing salbutamol dose 5

Remember that oral salbutamol has a slower onset of action compared to inhaled forms, making it more suitable for maintenance therapy rather than acute symptom relief.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Oral salbutamol therapy of asthma in young children.

The Journal of asthma research, 1977

Guideline

Asthma Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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