Laboratory Tests for Annual Physical in a 26-Year-Old Female with No Significant Medical History
For a healthy 26-year-old female with no significant past medical history, a focused set of laboratory tests including complete blood count, lipid panel, and cervical cancer screening is recommended for her annual physical examination. 1
Core Laboratory Tests
Essential Tests
- Complete Blood Count (CBC) - To screen for anemia, infection, and other hematologic abnormalities 2
- Comprehensive Metabolic Panel (CMP) - To assess electrolytes, liver and kidney function 2
- Lipid Profile - Total cholesterol, HDL, LDL, and triglycerides 2
- Cervical Cancer Screening (Pap test) - For women aged 21-65, screening should be done every 3 years with conventional or liquid-based Pap tests 1
Optional Tests Based on Risk Assessment
- Fasting Glucose or Hemoglobin A1C - If risk factors for diabetes are present (obesity, family history, etc.) 2
- Thyroid Function Tests (TSH) - If symptoms or family history of thyroid disease 2
- Urinalysis - To screen for kidney disease, urinary tract infections, or diabetes 2
Screening Guidelines by Category
Cancer Screening
- Cervical Cancer: Pap test every 3 years for women ages 21-29 1
- Breast Cancer: Clinical breast examination is recommended every 3 years for women in their 20s and 30s 1
- Note: Mammography is not recommended until age 40 1
Cardiovascular Risk Assessment
- Blood Pressure Measurement - Should be measured at least every 2 years 3
- Lipid Profile - Recommended as part of initial evaluation, especially with family history of premature cardiovascular disease 2
Reproductive Health
- Sexually Transmitted Infection (STI) Testing - Consider based on sexual history and risk factors
- Preconception Care - If planning pregnancy, consider additional testing including rubella immunity 1
Important Considerations
What to Avoid
- Unnecessary Testing: Avoid ordering tests without clear indications as they may lead to false positives and unnecessary follow-up 4
- Annual Complete Physical: Evidence does not support the need for a complete physical examination as traditionally defined for asymptomatic adults 3
Special Circumstances
- If family history suggests genetic disorders, consider targeted screening based on specific risks 1
- If planning pregnancy, additional preconception screening may be appropriate 1
Follow-Up Recommendations
- Review all laboratory results with patient
- Provide appropriate counseling based on findings
- Establish appropriate interval for next physical examination and laboratory testing
- Document any abnormal findings and follow-up plan
Remember that while these recommendations apply to the average 26-year-old female without significant medical history, clinical judgment should be used to add or modify tests based on specific symptoms, family history, or risk factors identified during the visit.