Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: September 4, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Lower Back Pain Worsened by Leg Movement

  • Single Most Likely Diagnosis
    • Lumbar Herniated Disc: This condition is a common cause of lower back pain that radiates to the legs and worsens with movement, especially bending, lifting, or twisting. The pain is often unilateral and can be accompanied by numbness, tingling, or weakness in the leg.
  • Other Likely Diagnoses
    • Lumbar Degenerative Disc Disease: Wear and tear on the spinal discs can lead to lower back pain that worsens with movement. This condition often presents with chronic pain and stiffness.
    • Lumbar Spinal Stenosis: Narrowing of the spinal canal can cause pain, numbness, or weakness in the back and legs, especially when walking or standing. Symptoms often improve with rest or bending forward.
    • Spondylolisthesis: A condition where a vertebra slips out of place, potentially causing lower back pain that worsens with movement, especially extension.
  • Do Not Miss Diagnoses
    • Cauda Equina Syndrome: A serious condition that occurs when the nerves in the spinal canal are compressed, leading to severe pain, numbness, and weakness in the legs, as well as potential bladder and bowel dysfunction. Immediate medical attention is required.
    • Spinal Infection (e.g., Osteomyelitis, Discitis): Infections of the spine can cause severe back pain, fever, and potentially serious complications if not promptly treated.
    • Spinal Tumor: Tumors in the spine can cause progressive back pain, weakness, and numbness, and require urgent medical evaluation.
  • Rare Diagnoses
    • Ankylosing Spondylitis: A chronic inflammatory disease that can cause lower back pain and stiffness, especially in young males. It can lead to fusion of the spine if not treated.
    • Osteoporotic Compression Fracture: Weakened bones can lead to fractures with minimal trauma, causing sudden onset of severe back pain.
    • Arteriovenous Malformation (AVM): A rare vascular anomaly that can cause back pain due to compression or bleeding, requiring immediate medical attention.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.