Typical Dosage for Dysport in Masseter Muscle
The typical dosage of Dysport for masseter muscle hypertrophy or bruxism is 100-140 units per side, with the specific dose determined by muscle thickness.
Dosing Guidelines
Botulinum toxin type A (Dysport) has emerged as an effective non-surgical treatment option for masseter muscle hypertrophy and bruxism. The dosing should follow these parameters:
- Standard dosage range: 100-140 units of Dysport per side 1
- Dosing considerations: Adjust based on:
- Muscle thickness (measured via ultrasonography)
- Severity of hypertrophy or bruxism
- Patient's previous response to treatment
Administration Technique
For optimal results and safety:
- Injection sites: Target specific regions of the masseter muscle
- Technique: Multiple small injections throughout the muscle belly
- Depth: Intramuscular injection
- Preparation: Dilution according to manufacturer's instructions
Treatment Protocol
- Initial assessment: Measure masseter muscle thickness using ultrasonography to determine appropriate dosing
- First treatment: Begin with dose in the 100-140 U range per side
- Follow-up: Assess response at 3-6 weeks post-injection 2
- Subsequent treatments:
- Typically administered every 4-6 months
- Dose may be decreased in subsequent visits as muscle size reduces 1
Efficacy and Expected Outcomes
- Onset of action: 1-2 weeks
- Peak effect: 3-4 weeks
- Duration of effect: Average of 19.1 weeks (range 6-78 weeks) 3
- Long-term effects: Progressive reduction in muscle volume with repeated treatments 1
- Success rate: High patient satisfaction reported in multiple studies 4, 5
Safety Considerations
- Common side effects: Mild local pain at injection site
- Rare complications: Dysphagia (reported in only 5.6% of cases) 3
- Contraindications:
- Allergy to botulinum toxin
- Infection at the proposed injection site
- Neuromuscular junction disorders 2
Clinical Pearls
- Patients with thicker masseter muscles tend to show better reduction effects 1
- Multiple treatment sessions yield progressive improvement in facial contour
- Combining treatment with splint therapy and relaxation techniques may enhance outcomes in cases of bruxism 6
- Ultrasonographic measurement before each treatment helps in determining appropriate dosage and tracking progress
This minimally invasive approach offers significant advantages over surgical management for masseter hypertrophy, with high rates of patient satisfaction and minimal side effects.