What is the treatment for nasal Candidiasis (fungal infection)?

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Last updated: March 12, 2025 • View editorial policy

From the Research

Nasal candidiasis is typically treated with antifungal medications, and for mild to moderate cases, topical antifungal treatments like clotrimazole cream (1%) or nystatin ointment applied inside the nostrils 2-3 times daily for 7-14 days are usually effective. The treatment approach for nasal candidiasis involves the use of antifungal agents, with the goal of reducing morbidity, mortality, and improving quality of life.

  • For mild to moderate cases, topical treatments are preferred due to their targeted action and lower risk of systemic side effects.
  • Topical antifungal treatments such as clotrimazole cream (1%) or nystatin ointment are applied inside the nostrils 2-3 times daily for 7-14 days, as supported by studies like 1 and 2.
  • In more severe or persistent infections, oral antifungal agents like fluconazole may be necessary, with a typical dose of 150mg taken orally once weekly for 2-4 weeks, as mentioned in 3. During treatment, it is essential to maintain good nasal hygiene by gently cleaning the nostrils with saline solution twice daily, avoiding irritants like harsh nasal sprays, and keeping the nasal passages moisturized with petroleum jelly or a saline gel, as these measures can help prevent reinfection and promote healing. If symptoms persist beyond two weeks of treatment or recur frequently, it is crucial to consult a healthcare provider, as this may indicate an underlying condition requiring additional treatment, as highlighted in 4 and 5.

References

Research

Candidiasis (oropharyngeal).

BMJ clinical evidence, 2012

Research

Candidiasis (oropharyngeal).

BMJ clinical evidence, 2013

Research

Candidiasis (oropharyngeal).

BMJ clinical evidence, 2009

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