Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: September 4, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for Back Pain

  • Single Most Likely Diagnosis
    • Musculoskeletal strain: This is the most common cause of back pain, often resulting from overuse, heavy lifting, or sudden movement. It affects the muscles and ligaments in the back.
  • Other Likely Diagnoses
    • Herniated disc: A condition where the soft inner gel of the disc leaks out through a tear in the outer layer, putting pressure on nerves and causing pain.
    • Degenerative disc disease: A condition where the spinal discs lose their cushioning ability, leading to pain and stiffness.
    • Spondylosis: A condition characterized by the degeneration of the spinal joints, which can cause back pain.
    • Osteoarthritis: Wear and tear on the joints in the spine, leading to pain and stiffness.
  • Do Not Miss Diagnoses
    • Spinal fracture: A break in one of the vertebrae, which can be caused by osteoporosis, trauma, or cancer.
    • Spinal infection (e.g., osteomyelitis, discitis): Infections of the spine that can cause severe back pain and potentially serious complications.
    • Cancer (e.g., metastatic disease, multiple myeloma): Back pain can be a symptom of various types of cancer that affect the spine.
    • Cauda equina syndrome: A condition where the nerves in the lower spine are compressed, leading to severe pain, numbness, and potentially permanent damage if not treated promptly.
    • Aortic dissection or abdominal aortic aneurysm: These are life-threatening conditions that can cause back pain, often severe and sudden.
  • Rare Diagnoses
    • Ankylosing spondylitis: A type of arthritis that affects the spine, leading to chronic pain and stiffness.
    • Spinal stenosis: Narrowing of the spinal canal, which can put pressure on the spinal cord and nerves.
    • Paget's disease of bone: A condition that affects bone remodeling, leading to enlarged and misshapen bones, which can cause back pain.
    • Osteoporotic compression fracture: A type of fracture that occurs when a vertebra collapses due to osteoporosis.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.