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Differential Diagnosis for Unilateral Dorsal Swelling of Hand

Single Most Likely Diagnosis

  • Ganglion Cyst: This is the most common cause of a lump on the wrist or hand, often presenting as a unilateral dorsal swelling. It is a benign cystic lesion that arises from the joint or tendon sheath.

Other Likely Diagnoses

  • Lipoma: A benign tumor composed of fat tissue, which can occur on the dorsal aspect of the hand and cause swelling.
  • Tenosynovitis: Inflammation of the tendon sheath, which can cause swelling, pain, and stiffness on the dorsal aspect of the hand.
  • Rheumatoid Nodule: A firm, painless nodule that can occur on the dorsal aspect of the hand in patients with rheumatoid arthritis.

Do Not Miss Diagnoses

  • Infection (e.g., Cellulitis or Abscess): Although less common, an infection can cause unilateral dorsal swelling of the hand and requires prompt treatment to prevent serious complications.
  • Tumor (e.g., Sarcoma): Although rare, a malignant tumor can present as a swelling on the dorsal aspect of the hand and is crucial to diagnose early for effective treatment.
  • Gout or Pseudogout: Crystal-induced arthropathies can cause sudden onset of swelling, pain, and redness on the dorsal aspect of the hand, and are important to diagnose to initiate appropriate treatment.

Rare Diagnoses

  • Giant Cell Tumor of the Tendon Sheath: A rare, benign tumor that can occur on the dorsal aspect of the hand and cause swelling.
  • Osteochondroma: A rare, benign bone tumor that can occur on the dorsal aspect of the hand and cause swelling.
  • Foreign Body Reaction: A rare cause of swelling on the dorsal aspect of the hand, which can occur as a reaction to a foreign body (e.g., a splinter).

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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