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Differential Diagnosis

The patient presents with heavy menstrual bleeding, irregular periods, and a history of medical and surgical conditions. The following differential diagnoses are considered:

  • Single most likely diagnosis
    • Uterine Fibroids: The patient's symptoms of heavy menstrual bleeding, large clots, and irregular periods are consistent with uterine fibroids. The presence of a copper IUD, which can sometimes cause heavy bleeding, may also be a contributing factor.
  • Other Likely diagnoses
    • Hormonal Imbalance: The patient's history of hyperthyroidism and recent hemithyroidectomy may be contributing to hormonal imbalances, leading to irregular periods and heavy bleeding.
    • Adenomyosis: The patient's symptoms of heavy menstrual bleeding, large clots, and irregular periods are also consistent with adenomyosis, a condition where tissue similar to the lining of the uterus grows into the uterine wall.
    • Copper IUD-related complications: The patient's copper IUD, which is due for replacement, may be causing or contributing to the heavy bleeding and irregular periods.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Uterine Cancer: Although less likely, uterine cancer must be considered in the differential diagnosis, especially given the patient's postmenopausal age and symptoms of heavy bleeding and irregular periods.
    • Bleeding Disorders: Bleeding disorders, such as von Willebrand disease, may be contributing to the patient's heavy menstrual bleeding and must be considered in the differential diagnosis.
  • Rare diagnoses
    • Uterine Arteriovenous Malformation (AVM): A rare condition where there is an abnormal connection between the arteries and veins in the uterus, which can cause heavy bleeding.
    • Uterine Sarcoma: A rare type of cancer that can cause heavy bleeding and irregular periods.

Each of these diagnoses requires further evaluation and investigation to determine the underlying cause of the patient's symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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