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Differential Diagnosis for STI

  • Single most likely diagnosis
    • Chlamydia: This is one of the most common sexually transmitted infections (STIs), often asymptomatic in its early stages, making it a likely candidate due to its prevalence.
  • Other Likely diagnoses
    • Gonorrhea: Similar to chlamydia, gonorrhea is a common STI that can be asymptomatic, especially in women, but can cause significant morbidity if untreated.
    • Syphilis: With its various stages and potential for severe complications if left untreated, syphilis is an important consideration in the differential diagnosis of STIs.
    • Herpes Simplex Virus (HSV): Given its prevalence and the fact that many infected individuals are unaware they have the virus, HSV is a plausible diagnosis.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • HIV: Human Immunodeficiency Virus infection is critical to diagnose early due to its significant impact on the immune system and the availability of effective antiretroviral therapy.
    • Hepatitis B and C: These viral infections can be transmitted sexually and, if untreated, can lead to severe liver disease, making them crucial not to miss.
  • Rare diagnoses
    • Lymphogranuloma Venereum (LGV): A less common STI caused by certain strains of chlamydia, LGV can cause significant morbidity, including proctitis and lymphadenopathy.
    • Granuloma Inguinale: Also known as Donovanosis, this is a rare STI characterized by genital ulcers, more commonly seen in tropical regions.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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