Differential Diagnosis for Groin Pain with Nausea

• Single Most Likely Diagnosis
  • Musculoskeletal strain or injury: This is often the most common cause of groin pain and can be accompanied by nausea due to pain severity or associated stress.
• Other Likely Diagnoses
  • Inguinal hernia: Can cause groin pain, especially if the hernia becomes incarcerated or strangulated, leading to nausea and vomiting.
  • Ovarian cyst or torsion (in females): These conditions can cause severe pelvic and groin pain, often accompanied by nausea.
  • Testicular torsion (in males): A medical emergency that causes severe groin pain and can lead to nausea and vomiting.
  • Kidney stone: While the primary pain is typically flank pain, it can radiate to the groin and be accompanied by nausea.
• Do Not Miss Diagnoses
  • Appendicitis: Although the primary location of pain is usually the right lower quadrant, it can start near the belly button and then move, and in some cases, radiate to the groin, accompanied by nausea and vomiting.
  • Ectopic pregnancy (in females): A life-threatening condition that can cause abdominal and groin pain, along with nausea and vomiting.
  • Ruptured abdominal aortic aneurysm: A medical emergency that can cause severe abdominal and back pain, potentially radiating to the groin, accompanied by nausea.
• Rare Diagnoses
  • Psoas abscess: An infection of the psoas muscle that can cause groin and lower back pain, often accompanied by systemic symptoms like nausea and fever.
  • Retroperitoneal hemorrhage: Bleeding in the retroperitoneal space can cause abdominal, back, and groin pain, along with nausea and potentially life-threatening complications.
  • Lymphoma or other malignancies: In rare cases, groin pain and nausea can be symptoms of lymphoma or other cancers affecting the lymph nodes or abdominal organs.