What should be included in a preoperative (pre-op) risk stratification?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: September 6, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Comprehensive Preoperative Risk Stratification Components

Preoperative risk stratification should include medical history review, physical examination, laboratory tests, functional capacity assessment, and cardiac risk evaluation to identify patients at elevated risk (≥1% risk of major adverse cardiovascular events) who may require additional testing or optimization. 1

Medical History Components

Patient-Specific Factors

  • Previous medical records review 2
  • Presence of congenital or acquired blood disorders 2
  • History of ischemic heart disease, heart failure, cerebrovascular disease 2
  • Medication history, particularly:
    • Anticoagulants (warfarin, clopidogrel, aspirin) 2
    • Beta-blockers 3
    • Insulin use and diabetes status 2
  • Vitamin or herbal supplement use affecting coagulation 2
  • Previous drug exposures that could cause allergic reactions (e.g., aprotinin) 2

Surgical Risk Factors

  • Urgency of procedure (emergency, urgent, time-sensitive, or elective) 1
  • Type of surgery (low risk <1%, intermediate risk 1-5%, high risk >5% for cardiac events) 2
  • Duration of procedure 2

Physical Examination

  • Assessment for organ ischemia 2
  • Evaluation for signs of coagulopathy 2
  • Cardiovascular examination 2
  • Pulmonary examination 2

Laboratory Testing

  • Hemoglobin/hematocrit 2
  • Coagulation profile (prothrombin time, platelet count) 2
  • Renal function (creatinine) 2
  • Additional laboratory tests based on patient's condition or institutional policy 2

Functional Capacity Assessment

  • Evaluation using two-flight stairs test or Duke Activity Status Index (DASI) 2, 1
  • Poor functional capacity defined as DASI <34 or <4 METs 1
  • Good functional capacity defined as DASI ≥34 or ≥4 METs 1

Cardiac Risk Evaluation

  • 12-lead ECG for intermediate and high-risk patients 2
  • Use of validated risk prediction tools:
    • Revised Cardiac Risk Index (RCRI) 2, 1
    • American College of Surgeons NSQIP risk calculator 1
    • AUB-HAS2 cardiovascular risk index 1

Special Populations Assessment

  • Frailty assessment for patients >70 years using validated tool 2
  • BMI evaluation (both high and low BMI associated with increased risk) 2
  • Pulmonary hypertension assessment (if suspected) 2

Risk Modifiers Identification

  • Severe valvular heart disease 1
  • Severe pulmonary hypertension 1
  • Elevated-risk congenital heart disease 1
  • Prior coronary stents/CABG 1
  • Recent stroke 1
  • Presence of cardiovascular implantable electronic devices 1

Biomarker Assessment (for high-risk patients)

  • BNP/NT-proBNP 1
  • Troponin 1

Additional Testing Based on Risk Level

  • For low-risk patients without risk modifiers: proceed to surgery without further cardiac testing 1
  • For elevated-risk patients without risk modifiers: consider 12-lead ECG 1
  • For patients with risk modifiers: consider appropriate team-based consultation and echocardiography 1
  • For patients with poor functional capacity: consider preoperative biomarker assessment 1
  • For patients with abnormal biomarkers: consider noninvasive stress testing or coronary CT angiography 1

Documentation Requirements

  • Patient preferences regarding blood transfusion 2
  • Discussion of risks and potential outcomes with patients and families 1
  • Multidisciplinary team involvement documentation for high-risk patients 1

Common Pitfalls to Avoid

  • Routine preoperative testing without clinical indication increases costs without improving outcomes 4
  • Discontinuing beta-blockers abruptly before surgery (can cause exacerbation of angina or MI) 3
  • Failure to identify and optimize modifiable risk factors before elective procedures 2
  • Over-reliance on a single risk calculator (no single calculator is universally superior) 1
  • Performing routine evaluation of left ventricular function in asymptomatic and clinically stable patients 1

By following this comprehensive approach to preoperative risk stratification, clinicians can identify patients at elevated risk for perioperative complications and implement appropriate management strategies to improve outcomes.

References

Guideline

Perioperative Risk Assessment

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Preoperative assessment.

Lancet (London, England), 2003

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.