From the Guidelines
The most recent and relevant gynecologic journal articles that contribute to understanding women's health are focused on the management of gynecologic cancers, including vulvar cancer, and the long-term effects of cancer treatments on survivors, as outlined in the 2024 NCCN Clinical Practice Guidelines in Oncology 1.
Key Developments in Gynecologic Cancer Management
- The management of gynecologic cancers, such as vulvar cancer, has evolved to include a range of treatments, including surgery, chemotherapy, and radiation therapy, each with its own set of potential long-term effects on survivors 1.
- Long-term survivors of gynecologic cancers may experience a range of physical and psychological effects, including sexual dysfunction, early menopause, and infertility, which require comprehensive care and management 1.
- The use of immunotherapy agents in gynecologic cancers is emerging, but the long-term effects of these treatments are not yet fully understood 1.
Importance of Survivorship Care Planning
- Survivorship care planning is critical for gynecologic cancer survivors, and should include regular general medical care, monitoring for cardiovascular risk factors, and encouragement of healthy lifestyle habits 1.
- Clinicians should comprehensively document the patient's history, including prior treatment history, and conduct a thorough physical examination and provide any necessary imaging and/or laboratory testing to assess the late and long-term effects of gynecologic cancers 1.
- Patients should be referred to appropriate specialty providers, such as physical therapy, pelvic floor therapy, sexual therapy, and psychotherapy, as needed, based on prior treatment history and assessed risk of developing late effects and/or existing concerns 1.
Recent Guidelines and Recommendations
- The American Cancer Society has published nutrition and physical activity guidelines for cancer survivors, including those with gynecologic cancers, which emphasize the importance of a healthy lifestyle in improving outcomes and reducing the risk of recurrence 1.
- The Gynecologic Cancer Intergroup (GCIG) has developed a consensus guideline for long-term survivorship in gynecologic cancer, which highlights the need for coordinated care and surveillance for recurrence and second primary cancers, as well as prevention and detection of post-treatment psychological and physical effects 1.
From the FDA Drug Label
The FDA drug label does not answer the question.
From the Research
Latest Gynecologic Journal Articles
The latest gynecologic journal articles have contributed significantly to the understanding of women's health, with a focus on various aspects of gynecologic cancer and women's health research. Some of the key findings include:
- Development of new medical treatments for epithelial ovarian cancer recurrence, including the use of antiangiogenic agents and PARP-inhibitors 2
- Major clinical research advances in gynecologic cancer, including targeted agents and immune checkpoint inhibitors for cervical, ovarian, and uterine corpus cancers 3
- Current and futuristic roadmap of ovarian cancer management, including novel approaches for early diagnosis, disease subtyping, prognosis, and therapy 4
- Recent developments in women's health research at the US National Institutes of Health, including policies, programs, and scientific advances that have informed and improved the health of women 5
Gynecologic Cancer Research
Gynecologic cancer research has made significant progress in recent years, with a focus on:
- Ovarian cancer, including the development of new treatments and the use of biobanking and analysis of patients' tumor samples to better understand the molecular aspects of the disease 2, 4
- Cervical cancer, including the use of targeted agents and immune checkpoint inhibitors, as well as adjuvant radiation therapy and concurrent/sequential chemoradiation therapy 3
- Uterine corpus cancer, including molecular classification and the use of molecular targeted agents, including immune checkpoint inhibitors 3
Women's Health Research
Women's health research has expanded to encompass all aspects of women's health, including:
- Preventive care, including the incorporation of preventive approaches in the annual well-woman visit and the identification of key elements of the well-woman examination 6
- Recent developments in women's health research at the US National Institutes of Health, including policies, programs, and scientific advances that have informed and improved the health of women 5