What is Proviro (Mesterolone)?

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Last updated: March 13, 2025View editorial policy

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From the Guidelines

Proviro, also known as Mesterolone, is a synthetic anabolic steroid that is used to treat low testosterone levels in men, but its use and efficacy are not well-established in the provided evidence. Without additional context about what "Proviro" refers to, I cannot provide specific recommendations about dosing, regimens, or usage. If you're asking about a specific product or treatment called Proviro, I would need more information about what it is intended to treat or its composition.

Key Points to Consider

  • The provided evidence does not directly mention Proviro or Mesterolone, but it discusses the use of testosterone therapy in men with low testosterone levels 1.
  • Testosterone therapy may provide small improvements in sexual functioning and quality of life in older men with low testosterone levels, but its long-term efficacy and safety are unknown 1.
  • The use of testosterone therapy in men without established conditions that cause permanent testicular or hypothalamic-pituitary dysfunction is not well-established, and its safety and efficacy may vary depending on the individual case 1.
  • It's essential to consult with a healthcare provider before using any medication or supplement, especially if it's a proprietary product or lacks rigorous clinical testing, as it may interact with medications or have unexpected side effects 1.

Recommendations

  • If you're seeking information about a specific medical condition or treatment option, providing more details would allow me to give you appropriate guidance.
  • Consult with a healthcare provider before using any medication or supplement, especially if it's a proprietary product or lacks rigorous clinical testing.
  • Be cautious when using any medication or supplement that lacks well-established safety and efficacy, as it may interact with medications or have unexpected side effects.

From the Research

Definition and Use of Proviro (Mesterolone)

  • Proviro, also known as Mesterolone, is an anabolic steroid that is used in the treatment of male hypogonadism 2.
  • It is a non-aromatizable androgen, which means it does not convert to estrogen in the body, and is sometimes used to treat symptoms of increased estrogen production, such as breast tenderness and gynecomastia 2.
  • Mesterolone is used as an alternative to testosterone replacement therapy in some cases, particularly when prostate safety is a concern 2.

Mechanism of Action and Effects

  • Mesterolone works by binding to androgen receptors in the body, which helps to increase testosterone levels and improve symptoms of hypogonadism 2.
  • It has been shown to be effective in improving sexual function, muscle mass, and bone density in hypogonadal men 3.
  • However, long-term use of Mesterolone can lead to bone loss, and it is recommended to switch to aromatizable preparations after a few months of therapy to prevent this 2.

Comparison to Other Treatments

  • Mesterolone is one of several treatment options available for male hypogonadism, including testosterone replacement therapy and other anabolic steroids 4, 3.
  • The choice of treatment depends on the individual patient's needs and medical history, and should be made in consultation with a healthcare professional 4, 3.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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