Differential Diagnosis for Liver Problem Causing Tiredness
Single Most Likely Diagnosis
- Chronic Hepatitis C: This is a common liver condition that can lead to fatigue due to the liver's decreased ability to detoxify the body and produce essential proteins. Hepatitis C is often asymptomatic in its early stages but can cause significant fatigue as the disease progresses.
Other Likely Diagnoses
- Non-Alcoholic Fatty Liver Disease (NAFLD): NAFLD is a condition where excess fat is stored in the liver, leading to inflammation and damage. It is associated with metabolic syndrome and can cause fatigue, among other symptoms.
- Alcoholic Liver Disease: Prolonged alcohol abuse can lead to liver damage, causing symptoms such as fatigue, jaundice, and abdominal swelling.
- Hemochromatosis: This genetic disorder leads to excessive iron accumulation in the body, including the liver, causing damage and potentially leading to fatigue, among other symptoms.
Do Not Miss Diagnoses
- Wilson's Disease: A rare genetic disorder that causes copper accumulation in the liver, brain, and other organs. If untreated, it can lead to severe liver damage and neurological symptoms. Early diagnosis is crucial for effective treatment.
- Autoimmune Hepatitis: A condition where the body's immune system attacks liver cells, leading to inflammation and damage. It can present with fatigue, jaundice, and other symptoms, and requires prompt treatment to prevent liver failure.
- Budd-Chiari Syndrome: A rare condition caused by blood clots in the hepatic veins, leading to liver congestion, damage, and potentially life-threatening complications if not recognized and treated promptly.
Rare Diagnoses
- Primary Biliary Cholangitis (PBC): A chronic liver disease characterized by the progressive destruction of the bile ducts within the liver, leading to fatigue, jaundice, and other symptoms.
- Primary Sclerosing Cholangitis (PSC): A rare disease that leads to scarring and narrowing of the bile ducts, causing fatigue, jaundice, and increased risk of liver cancer and infections.
- Alpha-1 Antitrypsin Deficiency: A genetic disorder that can cause liver disease and lung disease, leading to symptoms such as fatigue, shortness of breath, and jaundice.