Differential Diagnosis for Lacie Blanching Reticular Rash
Single Most Likely Diagnosis
- Livedo Reticularis: This condition is characterized by a mottled, reticular rash due to impaired blood flow, which can be caused by various factors such as cold temperatures, vasculitis, or thrombophilia. The description of a lacie blanching reticular rash on multiple extremities and trunk is highly suggestive of livedo reticularis.
Other Likely Diagnoses
- Vasculitis: Conditions like polyarteritis nodosa, lupus, or rheumatoid arthritis can cause a reticular rash due to inflammation of blood vessels.
- Thrombophilia: Hypercoagulable states, such as antiphospholipid syndrome, can lead to livedo reticularis and other skin manifestations.
- Raynaud's Phenomenon: This condition causes blood vessels to constrict in response to cold or stress, leading to a reticular rash and other symptoms.
Do Not Miss Diagnoses
- Antiphospholipid Syndrome: A hypercoagulable state that can cause livedo reticularis, as well as other serious complications like stroke or pulmonary embolism.
- Disseminated Intravascular Coagulation (DIC): A life-threatening condition that can cause a reticular rash, as well as other symptoms like bleeding or thrombosis.
- Sepsis: A severe infection that can cause a reticular rash, as well as other symptoms like fever, hypotension, or organ dysfunction.
Rare Diagnoses
- Sneddon's Syndrome: A rare condition characterized by livedo reticularis and stroke-like symptoms.
- Ehlers-Danlos Syndrome: A genetic disorder that can cause skin hyperextensibility, joint hypermobility, and other symptoms, including a reticular rash.
- Cryoglobulinemia: A rare condition caused by abnormal proteins in the blood that can cause a reticular rash, as well as other symptoms like purpura or neuropathy.