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Differential Diagnosis for Left Knee Swelling in a 76-Year-Old Female Following a Fall

Single Most Likely Diagnosis

  • Osteoarthritis with possible meniscal tear or ligament sprain: Given the patient's age and the history of a fall, it's plausible that the injury exacerbated existing osteoarthritis or caused a meniscal tear or ligament sprain, leading to swelling and pain.

Other Likely Diagnoses

  • Hemarthrosis: A fall could cause bleeding into the joint space, especially if there was trauma to the knee.
  • Bursitis: Inflammation of the bursae around the knee joint could be caused by the fall or overuse in compensating for the injury.
  • Tendinitis: Tendons around the knee could be inflamed due to the fall or subsequent altered gait.
  • Fracture: Although it might seem obvious, a fracture, especially of the patella or tibial plateau, could be a cause of swelling and should be considered, especially if there was significant trauma.

Do Not Miss Diagnoses

  • Deep Vein Thrombosis (DVT): Given the patient's age and recent history of immobility following a fall, DVT is a critical diagnosis not to miss, as it can lead to pulmonary embolism.
  • Infection (septic arthritis): Especially if the patient has been immobile or has compromised skin integrity, infection of the joint is a serious and potentially deadly condition that must be ruled out.
  • Osteonecrosis: If the blood supply to the bone was compromised during the fall, osteonecrosis could occur, leading to bone death and potentially severe arthritis.

Rare Diagnoses

  • Tumor (primary or metastatic): Although rare, a tumor could cause swelling and pain in the knee, especially in an older adult.
  • Rheumatologic conditions (e.g., rheumatoid arthritis, lupus): These conditions can cause knee swelling but would typically be accompanied by other systemic symptoms.
  • Complex regional pain syndrome (CRPS): A condition characterized by chronic pain, inflammation, and hypersensitivity following an injury, which could be considered if other diagnoses are ruled out and symptoms persist.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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