From the Research
Prevagen has not been proven effective for improving memory or cognitive function despite its marketing claims. The active ingredient, apoaequorin, is a protein derived from jellyfish that the manufacturer claims supports brain function, but there is insufficient scientific evidence to support this, as noted in a recent analysis of clinical evidence 1. The Federal Trade Commission has challenged the company's claims about Prevagen's effectiveness, noting that the protein is likely broken down during digestion before reaching the brain.
Key Points
- The single company-sponsored study often cited to support Prevagen's benefits had methodological flaws and showed no overall benefit when analyzed properly.
- For those concerned about memory or cognitive issues, better approaches include:
- Regular physical exercise
- Maintaining a healthy diet rich in omega-3 fatty acids
- Engaging in mental stimulation
- Getting adequate sleep
- Managing stress
- If experiencing significant memory concerns, consulting a healthcare provider is recommended rather than relying on supplements with questionable efficacy like Prevagen.
Alternative Approaches
Studies have shown that a combination of omega-3 fatty acid supplementation, aerobic exercise, and cognitive stimulation can prevent decline in gray matter volume of the frontal, parietal, and cingulate cortex in patients with mild cognitive impairment 2. Additionally, a multifaceted intervention including exercise, nutritional advice, and cognitive training may be beneficial for preventing cognitive decline in elderly adults with memory complaints 3.
Conclusion Not Applicable
Instead, the focus is on the direct answer and the evidence supporting it, without a need for a concluding section. The most recent and highest quality study, 1, provides the basis for the recommendation against using Prevagen for improving memory or cognitive function.