From the Research
Entyvio (vedolizumab) can potentially cause coughing as a side effect, though it's not among the most common reactions. Coughing has been reported in clinical trials and post-marketing surveillance, but it occurs less frequently than other side effects like headaches, joint pain, or upper respiratory tract infections. Entyvio works by targeting specific gut-selective integrins to reduce inflammation in inflammatory bowel diseases like Crohn's disease and ulcerative colitis. Since it has a gut-selective mechanism of action, respiratory side effects are generally less common compared to other biologic medications. If you develop a persistent cough while taking Entyvio, it's essential to contact your healthcare provider, as it could potentially indicate an allergic reaction, infection, or other medical issue that needs evaluation. Don't stop taking Entyvio without medical guidance, as discontinuing treatment could lead to disease flares.
Some key points to consider:
- The exact mechanism of cough associated with Entyvio is not well understood, but it may be related to the drug's effects on the immune system 1.
- Cough is a common symptom in various respiratory and non-respiratory conditions, and its association with Entyvio may be coincidental or related to the underlying disease being treated 2.
- Other medications, such as ACE inhibitors, have been associated with cough as a side effect, but the mechanism and incidence may differ from Entyvio 3.
- If you experience a persistent cough while taking Entyvio, your healthcare provider may consider alternative causes and treat accordingly, rather than attributing it solely to the medication 4, 5.
It's crucial to prioritize your health and consult your healthcare provider if you have concerns about coughing or any other side effects while taking Entyvio.