Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: September 9, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for a Painful Tender 3 Breast Lump in Armpit

Single Most Likely Diagnosis

  • Breast cyst or abscess: This is the most likely diagnosis due to the description of a painful tender lump in the armpit area, which could be related to the breast tissue. Breast cysts are common and can become infected, leading to an abscess.

Other Likely Diagnoses

  • Lymphadenitis: Inflammation of the lymph nodes in the armpit can cause painful lumps, which could be related to an infection or other inflammatory conditions.
  • Lipoma: A benign fatty tumor that can occur in the armpit area, potentially causing a lump, although it is typically painless.
  • Infected sebaceous cyst: A sebaceous cyst that becomes infected can cause a painful lump in the armpit area.

Do Not Miss Diagnoses

  • Breast cancer with axillary metastasis: Although less likely, it is crucial not to miss breast cancer that has spread to the axillary lymph nodes, as it requires prompt treatment.
  • Lymphoma: Both Hodgkin's and non-Hodgkin's lymphoma can present with lymphadenopathy (enlarged lymph nodes) in the armpit, which could be painful.

Rare Diagnoses

  • Hygroma: A rare, benign condition that can cause a lump in the armpit, typically presenting as a soft, cystic mass.
  • Neurofibroma: A rare tumor of the nerve tissue that can occur in the armpit, potentially causing a lump.
  • Axillary schwannoma: A rare, benign tumor of the nerve sheath that can occur in the armpit, causing a lump.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.