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Differential Diagnosis for Wart

  • Single most likely diagnosis
    • Verruca vulgaris (common wart): This is the most common type of wart and is caused by the human papillomavirus (HPV). It typically presents as a rough, hyperkeratotic lesion on the skin.
  • Other Likely diagnoses
    • Verruca plana (flat wart): These are flat, smooth lesions that are also caused by HPV. They often appear in clusters and can be found on the face, hands, or feet.
    • Verruca plantaris (plantar wart): This type of wart occurs on the sole of the foot and can be painful. It is also caused by HPV.
    • Seborrheic keratosis: A benign growth that can resemble a wart, but is not caused by a virus. It is more common in older adults.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Squamous cell carcinoma: A type of skin cancer that can resemble a wart. It is more common in areas exposed to the sun and can be aggressive if not treated.
    • Keratoacanthoma: A low-grade malignancy that can resemble a wart. It typically grows rapidly and can resolve on its own, but can also be aggressive.
  • Rare diagnoses
    • Epidermodysplasia verruciformis: A rare genetic disorder that causes an abnormal susceptibility to HPV, leading to the development of multiple warts.
    • Molluscum contagiosum: A viral infection that causes small, pearly lesions that can resemble warts. It is highly contagious and can be spread by skin-to-skin contact.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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