What is the protocol for managing pain?

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Last updated: September 9, 2025View editorial policy

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Pain Management Protocol

Pain management requires a comprehensive biopsychosocial approach that combines assessment, pharmacological interventions, non-pharmacological strategies, and regular reevaluation to effectively reduce pain intensity, improve function, and enhance quality of life. 1

Initial Assessment

  1. Pain Evaluation:

    • Assess pain intensity using validated tools
    • Determine pain characteristics (location, quality, duration)
    • Identify pain triggers and alleviating factors
    • Evaluate functional impact on daily activities
  2. Risk Stratification:

    • Screen for risk of pain persistence using tools like STarTBack for back pain 1
    • Identify psychosocial factors (anxiety, depression, catastrophizing)
    • Assess for substance use disorders or medication misuse risk
  3. Diagnostic Workup:

    • Perform targeted investigations based on clinical presentation
    • Avoid excessive testing; use simple tests like X-rays for trauma or ESR for inflammatory conditions 1
    • Focus on moving away from continuous cycle of investigations

Treatment Approach

Non-Pharmacological Interventions (First-Line)

  1. Physical/Restorative Therapy:

    • Exercise therapy for low back pain and other chronic pain conditions 1, 2
    • Progressive resistance training and weight-bearing exercises
    • Physical and occupational therapy to improve function and reduce disability
  2. Psychological Interventions:

    • Cognitive Behavioral Therapy (CBT) to promote adaptive behaviors 1, 2
    • Biofeedback and relaxation training for pain management
    • Mindfulness-based stress reduction programs
  3. Patient Education:

    • Explain pain neurophysiology using visual aids, metaphors, and diagrams 1, 2
    • Distinguish between acute and chronic pain mechanisms
    • Set realistic treatment goals focused on function rather than complete pain elimination
  4. Alternative Therapies:

    • Yoga for musculoskeletal pain 2
    • Acupuncture for trial in chronic pain conditions 2
    • Local therapies (heat/cold packs, massage)

Pharmacological Management

  1. First-Line Medications:

    • Non-opioid analgesics (acetaminophen, NSAIDs) 1, 2
    • Gabapentin for neuropathic pain (titrate to 2400mg/day in divided doses) 2
    • Topical agents (lidocaine, capsaicin) for peripheral neuropathic pain 1
  2. Second-Line Medications:

    • Antidepressants: Tricyclic antidepressants and SNRIs for neuropathic pain 1, 2
    • Anticonvulsants (α-2-delta calcium-channel antagonists, sodium-channel antagonists) 1
    • Muscle relaxants for specific conditions with muscle spasm 1
  3. Third-Line Medications:

    • Opioids should only be considered after failure of other options 2, 3
    • If prescribed, implement careful monitoring and clear tapering plan
    • For opioid tapering, reduce by 10-25% of total daily dose every 2-4 weeks 3

Interventional Approaches (For Refractory Pain)

  1. Nerve Blocks and Ablation:

    • Consider for well-localized pain syndromes 1
    • Radiofrequency ablation for bone pain 1
    • Vertebral augmentation for vertebral compression fractures 1
  2. Neuromodulation:

    • Transcutaneous electrical nerve stimulation (TENS) 2
    • Neurostimulation for chemotherapy-induced peripheral neuropathies and neuralgias 1

Monitoring and Follow-up

  1. Regular Reassessment:

    • Review patient management plan within 6 months 1
    • Evaluate treatment efficacy using validated tools
    • Monitor for side effects and adverse events
  2. Treatment Adjustments:

    • Consider change in treatment if inadequate response
    • Refer to specialist for complex or refractory cases
    • Implement multimodal approach combining therapies

Special Considerations

  1. Cancer Pain:

    • Requires more aggressive management approach 1
    • Consider disease-modifying treatments (radiation therapy)
    • May require earlier consideration of opioids and interventional techniques
  2. Neuropathic Pain:

    • Prioritize anticonvulsants and antidepressants 1, 2, 4
    • Consider topical agents for peripheral neuropathic pain
    • May benefit from specialized interventional approaches

Common Pitfalls to Avoid

  1. Over-reliance on opioids - Use as last resort after exhausting other options 2, 3
  2. Underutilization of non-pharmacological approaches - These should be first-line 2
  3. Failure to address psychological aspects - Pain has significant psychological components 1
  4. Inadequate patient education - Patients need to understand their pain 1, 2
  5. Lack of regular reassessment - Treatment plans require ongoing evaluation 1

By following this structured protocol, healthcare providers can effectively manage pain while minimizing risks and optimizing patient outcomes. The multimodal approach combining physical, psychological, and pharmacological interventions offers the best chance for successful pain management.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Chronic Pain Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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