From the Guidelines
No, Signal Relief Patch does not contain capsaicin. The Signal Relief Patch is a non-drug, non-transdermal patch that uses nanotechnology to allegedly provide pain relief through a different mechanism than traditional pain relief patches. Unlike capsaicin patches (such as Qutenza or over-the-counter capsaicin products), which work by depleting substance P in nerve endings to reduce pain signals, Signal Relief claims to work by absorbing and reflecting the body's electrical signals associated with pain. The patch contains no active pharmaceutical ingredients, including no capsaicin, lidocaine, menthol, or other topical analgesics. It's marketed as a drug-free alternative that doesn't introduce any substances into the body. This makes it different from medication-based patches that deliver active ingredients through the skin. If you're specifically looking for capsaicin-based pain relief, you would need to choose a different product explicitly labeled as containing capsaicin, as capsaicin has been shown to be effective in treating pain in diabetic neuropathy, as reported in a high-quality study 1. Some key points to consider when choosing a pain relief product include:
- The mechanism of action: capsaicin works by depleting substance P in nerve endings, while Signal Relief uses nanotechnology to absorb and reflect electrical signals associated with pain.
- The presence of active pharmaceutical ingredients: Signal Relief contains no active ingredients, while capsaicin patches contain capsaicin as the active ingredient.
- The potential benefits and risks: capsaicin has been shown to be effective in treating pain in diabetic neuropathy, but may cause adverse effects such as burning or stinging, as reported in a study 2. In contrast, Signal Relief is marketed as a drug-free alternative with no introduced substances, but its effectiveness and safety have not been established in high-quality studies. Therefore, if you are looking for a capsaicin-based pain relief product, you should choose a different product that explicitly contains capsaicin, as supported by the most recent and highest quality study 1.
From the FDA Drug Label
Active Ingredient Purpose Capsaicin 0.035% External Analgesic The Signal Relief Patch does not contain capsaicin, according to the provided information, the label is for a different product named capsaicin (TOP), not Signal Relief Patch 3.
From the Research
Signal Relief Patch Ingredients
- The provided studies do not mention the Signal Relief Patch containing capsaicin 4, 5, 6, 7, 8.
- The studies focus on the capsaicin 8% patch (Qutenza) and its effectiveness in treating peripheral neuropathic pain, but do not provide information on the Signal Relief Patch.
Capsaicin 8% Patch
- The capsaicin 8% patch is a licensed treatment in the EU/UK for neuropathic pain and has been shown to be safe and effective in providing pain relief for patients with chemotherapy-induced peripheral neuropathy (CIPN) 6, 8.
- The patch can provide pain relief for up to 3 months or longer after a single 30-60 minute application 7, 8.
- The side-effects of the capsaicin 8% patch are transient and restricted to the time around patch application 6, 8.
Conclusion Not Available
There are no research papers to assist in answering the question of whether the Signal Relief Patch contains capsaicin.